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- W27785711 abstract "In the quest to minimize the occurrence of spinal cord injury (SCI) secondary to resection of descending thoracic and thoracoabdominal aortic aneurysms (TAAA), we have undertaken a reevaluation of the anatomy and physiology of the circulation to the spinal cord. To this end, we have performed descriptive and morphometric anatomic studies in pigs, both in the native state and at various times after extensive segmental artery (SA) ligation.1,2 We have also monitored the pressure in the distal stump of lumbar arteries after extensive SA resection using various experimental protocols in pigs, and have monitored distal lumbar artery pressure in patients during and after extensive TAAA resection.3,4These anatomic and physiologic studies have shown unequivocally the existence of an extensive collateral network of vessels that supply the spinal cord, as well as the adjacent paraspinous muscles. This network has been revealed as a dynamic entity that adapts to the elimination of direct SA input—resulting from simulated experimental or clinical aneurysm resection—by a process of remodeling to maintain spinal cord viability and to guard against the development of subsequent SCI. We have termed this new understanding of the spinal cord blood supply and its adaptations the Collateral Network Concept." @default.
- W27785711 created "2016-06-24" @default.
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- W27785711 date "2010-01-01" @default.
- W27785711 modified "2023-09-23" @default.
- W27785711 title "The collateral network concept: minimizing paraplegia secondary to thoracoabdominal aortic aneurysm resection." @default.
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