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- W2778635883 abstract "Anacardium occidentale is well established in folklore medicine and is reputed to be effective against renal andskin infections and is also used to treat tooth decay and acne. This study was carried out to explore thepharmacognostic and anti-diabetic activity of the ethanol extract of Anacardium occidentale root in both normal andStreptozotocin induced diabetic mice. The diverse features of the powdered root were observed macroscopicallyusing the standard description of terms. The powder is light brown in colour, rough to touch with characteristicodour and taste. Some of the characteristic features of the plant observed microscopically were multicellularmultiseriate medullary rays crossing parenchymatous cells, prism of calcium oxalate crystals spread across the celland fibre groups forming sheaths with prisms on them. The crude drug was found to have a moisture content of 15%w/w while the total ash, water soluble ash and acid insoluble ash values were 2.67% w/w, 34% w/w and 10% w/wrespectively. Phytochemical evaluation of the extract revealed the presence of alkaloid, tannins, anthraquinones,flavonoid, and terpenes/steroids. Streptozotocin-induced diabetic and non-diabetic mice were administeredintraperitoneally with ethanol extract of the root at 500 mg/kg, 250 mg/kg and 125 mg/kg respectively, for six hours.There was a significant (p<0.05) reduction in the level of blood glucose of the mice after administration .The resultsfrom this study suggest that the ethanolic extract of the root possesses some hypoglycemic properties and couldtherefore have potential for diabetes management." @default.
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- W2778635883 date "2017-01-01" @default.
- W2778635883 modified "2023-09-26" @default.
- W2778635883 title "Pharmacognostic Studies and Antidiabetic Evaluation of the Ethanolic Root Extract of Anacardium occidentale Linn (Anacardiaceae) in Mice" @default.
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