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- W2778760721 endingPage "117822341774981" @default.
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- W2778760721 abstract "Vitamin D (the sunshine vitamin) plays a vital role in calcium homeostasis, skeletal metabolism, and immune, cardiovascular, and reproductive systems’ functions. The worldwide prevalence of vitamin D deficiency is approximately 1 billion. Vitamin D deficiency is a serious health problem with numerous health consequences; it is associated with diabetes, rheumatic arthritis, Parkinson, Alzheimer diseases, osteomalacia, osteoporosis, and fractures in adults and cancers. Many reports showed an inverse association between serum vitamin D concentration and incidence of several cancers, including breast, colorectal, kidney, lung, and pancreatic. About 20 different cancers have incidence rates inversely related to solar UV-B doses and serum vitamin D concentration. Considering the rising incidence of breast cancer and high prevalence of vitamin D deficiency, this review aimed to reflect an association between serum vitamin D concentration and breast cancer risk, reveal the link between vitamin D receptor genetic polymorphisms and breast cancer risk, and review the relationship between vitamin D level, breast cancer risk, and prognostic factors such as tumor stage, grade, size, lymph node involvement, and hormone receptor status." @default.
- W2778760721 created "2018-01-05" @default.
- W2778760721 creator A5014989604 @default.
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- W2778760721 date "2017-01-01" @default.
- W2778760721 modified "2023-10-16" @default.
- W2778760721 title "Vitamin D and Breast Cancer: Latest Evidence and Future Steps" @default.
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- W2778760721 doi "https://doi.org/10.1177/1178223417749816" @default.
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