FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2778889606> ?p ?o ?g. }

• W2778889606 endingPage "81" @default.
• W2778889606 startingPage "76" @default.
• W2778889606 abstract "Regardless of different sources, methods or devices which are applied for preparation of therapeutic platelets, these products are generally isolated from whole blood by the sedimentation techniques which are based on PRP or buffy coat (BC) separation. As a general fact, platelet preparation and storage are also associated with some deleterious changes that known as platelet storage lesion (PSL). Although these alternations in platelet functional activity are aggravated during storage, whether technical issues within preparation can affect integrin activation and platelet adhesion to fibrinogen were investigated in this study.PRP- and BC-platelet concentrates (PCs) were subjected to flowcytometry analysis to examine the expression of platelet activation marker, P-selectin as well as active confirmation of the GPIIb/IIIa (αIIbβ3) on day 0, 1, 3 and 5 post-storage. Platelet adhesion to fibrinogen matrix was evaluated by fluorescence microscopy. Glucose concentration and LDH activity were also measured by colorimetric methods.The increasing P-selectin expression during storage was in a reverse correlation with PAC-1 binding (r = -0.67; p = .001). PRP-PCs showed the higher level of P-selectin expression than BC-PCs, whereas the levels of PAC-1 binding and platelet adhesion to fibrinogen matrix were significantly lower in PRP-PCs. Higher levels of active confirmation of the GPIIb/IIIa in BC-PCs were also associated with greater concentration of glucose in these products.We demonstrated the superior capacities of integrin activation and adhesion to fibrinogen for BC-PCs compared to those of PRP-PCs. These findings may provide more advantages for BC method of platelet preparation." @default.
• W2778889606 created "2018-01-05" @default.
• W2778889606 creator A5024984048 @default.
• W2778889606 creator A5054493946 @default.
• W2778889606 creator A5075172075 @default.
• W2778889606 date "2018-02-01" @default.
• W2778889606 modified "2023-10-17" @default.
• W2778889606 title "Superior integrin activating capacity and higher adhesion to fibrinogen matrix in buffy coat-derived platelet concentrates (PCs) compared to PRP-PCs" @default.
• W2778889606 cites W1534390354 @default.
• W2778889606 cites W1783401755 @default.
• W2778889606 cites W1944326398 @default.
• W2778889606 cites W1954569381 @default.
• W2778889606 cites W1970136444 @default.
• W2778889606 cites W1980051845 @default.
• W2778889606 cites W1981258266 @default.
• W2778889606 cites W1986075774 @default.
• W2778889606 cites W2000558617 @default.
• W2778889606 cites W2013544298 @default.
• W2778889606 cites W2014235833 @default.
• W2778889606 cites W2023438928 @default.
• W2778889606 cites W2025634312 @default.
• W2778889606 cites W2040698128 @default.
• W2778889606 cites W2042659329 @default.
• W2778889606 cites W2052823603 @default.
• W2778889606 cites W2053867901 @default.
• W2778889606 cites W2060264965 @default.
• W2778889606 cites W2072920657 @default.
• W2778889606 cites W2079461704 @default.
• W2778889606 cites W2092284194 @default.
• W2778889606 cites W2100269967 @default.
• W2778889606 cites W2101312250 @default.
• W2778889606 cites W2117138221 @default.
• W2778889606 cites W2154253381 @default.
• W2778889606 cites W2441496056 @default.
• W2778889606 cites W2480310889 @default.
• W2778889606 cites W2532545424 @default.
• W2778889606 doi "https://doi.org/10.1016/j.transci.2017.12.003" @default.
• W2778889606 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29292029" @default.
• W2778889606 hasPublicationYear "2018" @default.
• W2778889606 type Work @default.
• W2778889606 sameAs 2778889606 @default.
• W2778889606 citedByCount "4" @default.
• W2778889606 countsByYear W27788896062019 @default.
• W2778889606 countsByYear W27788896062020 @default.
• W2778889606 countsByYear W27788896062022 @default.
• W2778889606 crossrefType "journal-article" @default.
• W2778889606 hasAuthorship W2778889606A5024984048 @default.
• W2778889606 hasAuthorship W2778889606A5054493946 @default.
• W2778889606 hasAuthorship W2778889606A5075172075 @default.
• W2778889606 hasConcept C1491633281 @default.
• W2778889606 hasConcept C153911025 @default.
• W2778889606 hasConcept C16685009 @default.
• W2778889606 hasConcept C178790620 @default.
• W2778889606 hasConcept C185592680 @default.
• W2778889606 hasConcept C195687474 @default.
• W2778889606 hasConcept C203014093 @default.
• W2778889606 hasConcept C2778285947 @default.
• W2778889606 hasConcept C2779036427 @default.
• W2778889606 hasConcept C2780009322 @default.
• W2778889606 hasConcept C2993802102 @default.
• W2778889606 hasConcept C3018697912 @default.
• W2778889606 hasConcept C55493867 @default.
• W2778889606 hasConcept C56701166 @default.
• W2778889606 hasConcept C71924100 @default.
• W2778889606 hasConcept C84416704 @default.
• W2778889606 hasConcept C86803240 @default.
• W2778889606 hasConcept C89560881 @default.
• W2778889606 hasConceptScore W2778889606C1491633281 @default.
• W2778889606 hasConceptScore W2778889606C153911025 @default.
• W2778889606 hasConceptScore W2778889606C16685009 @default.
• W2778889606 hasConceptScore W2778889606C178790620 @default.
• W2778889606 hasConceptScore W2778889606C185592680 @default.
• W2778889606 hasConceptScore W2778889606C195687474 @default.
• W2778889606 hasConceptScore W2778889606C203014093 @default.
• W2778889606 hasConceptScore W2778889606C2778285947 @default.
• W2778889606 hasConceptScore W2778889606C2779036427 @default.
• W2778889606 hasConceptScore W2778889606C2780009322 @default.
• W2778889606 hasConceptScore W2778889606C2993802102 @default.
• W2778889606 hasConceptScore W2778889606C3018697912 @default.
• W2778889606 hasConceptScore W2778889606C55493867 @default.
• W2778889606 hasConceptScore W2778889606C56701166 @default.
• W2778889606 hasConceptScore W2778889606C71924100 @default.
• W2778889606 hasConceptScore W2778889606C84416704 @default.
• W2778889606 hasConceptScore W2778889606C86803240 @default.
• W2778889606 hasConceptScore W2778889606C89560881 @default.
• W2778889606 hasIssue "1" @default.
• W2778889606 hasLocation W27788896061 @default.
• W2778889606 hasLocation W27788896062 @default.
• W2778889606 hasOpenAccess W2778889606 @default.
• W2778889606 hasPrimaryLocation W27788896061 @default.
• W2778889606 hasRelatedWork W1491553011 @default.
• W2778889606 hasRelatedWork W1982739621 @default.
• W2778889606 hasRelatedWork W2023279715 @default.
• W2778889606 hasRelatedWork W2052405788 @default.
• W2778889606 hasRelatedWork W2058936350 @default.
• W2778889606 hasRelatedWork W2071317817 @default.
• W2778889606 hasRelatedWork W2557966141 @default.
• W2778889606 hasRelatedWork W2776749095 @default.

• next