Matches in SemOpenAlex for { <https://semopenalex.org/work/W2779137890> ?p ?o ?g. }
- W2779137890 endingPage "129" @default.
- W2779137890 startingPage "119" @default.
- W2779137890 abstract "Non-functioning pituitary neuroendocrine tumors do not cause endocrine symptoms related to hypersecretion of adenohypophyseal hormones and are clinically characterized by symptoms due to growing sellar tumor mass. Histopathological classification of this tumor group has always been challenging due to their heterogeneity, limited knowledge on their biology, and diverse methodological problems. We have searched PubMed database for data related to the histopathological classification of non-functioning pituitary tumors and methods for its application. Principles of the classification and grading presented in the recently released 4th edition of the World Health Organization classification of endocrine tumors have been summarized. Based on the expression of anterior pituitary hormones and pituitary specific transcription factors, gonadotroph tumors dominate within the group of clinically non-functioning tumors, followed by corticotroph type; however, other less common types of the non-functioning tumors can be identified. Assessment of tumor cell proliferation is important to identify “high-risk adenomas.” A few subtypes of non-functioning tumors belong to the category of potentially aggressive tumors, independent of the cell proliferation rate. Here, we present up to date criteria for the classification of clinically non-functioning pituitary tumors, offer a diagnostic approach for the routine clinical use, and emphasize a need for inclusion of prognostic and predictive markers in the classification." @default.
- W2779137890 created "2018-01-05" @default.
- W2779137890 creator A5023028346 @default.
- W2779137890 creator A5031617364 @default.
- W2779137890 creator A5088126776 @default.
- W2779137890 date "2017-12-23" @default.
- W2779137890 modified "2023-10-11" @default.
- W2779137890 title "Histopathological classification of non-functioning pituitary neuroendocrine tumors" @default.
- W2779137890 cites W1232084036 @default.
- W2779137890 cites W1925935443 @default.
- W2779137890 cites W1969036827 @default.
- W2779137890 cites W1970816475 @default.
- W2779137890 cites W1976596739 @default.
- W2779137890 cites W1976633781 @default.
- W2779137890 cites W1979964623 @default.
- W2779137890 cites W1981171396 @default.
- W2779137890 cites W1981498768 @default.
- W2779137890 cites W1982756072 @default.
- W2779137890 cites W1983083898 @default.
- W2779137890 cites W1988898379 @default.
- W2779137890 cites W1992362172 @default.
- W2779137890 cites W1993419727 @default.
- W2779137890 cites W1994400093 @default.
- W2779137890 cites W1994644015 @default.
- W2779137890 cites W1998829259 @default.
- W2779137890 cites W1999582566 @default.
- W2779137890 cites W2004826712 @default.
- W2779137890 cites W2005493471 @default.
- W2779137890 cites W2016970675 @default.
- W2779137890 cites W2024596477 @default.
- W2779137890 cites W2027981735 @default.
- W2779137890 cites W2030604268 @default.
- W2779137890 cites W2030950835 @default.
- W2779137890 cites W2035953722 @default.
- W2779137890 cites W2036437059 @default.
- W2779137890 cites W2047245583 @default.
- W2779137890 cites W2052506678 @default.
- W2779137890 cites W2052640332 @default.
- W2779137890 cites W2057232344 @default.
- W2779137890 cites W2058254927 @default.
- W2779137890 cites W2060271143 @default.
- W2779137890 cites W2062317084 @default.
- W2779137890 cites W2062502773 @default.
- W2779137890 cites W2065499606 @default.
- W2779137890 cites W2074316110 @default.
- W2779137890 cites W2077574437 @default.
- W2779137890 cites W2078555121 @default.
- W2779137890 cites W2085419335 @default.
- W2779137890 cites W2087248843 @default.
- W2779137890 cites W2100396774 @default.
- W2779137890 cites W2105922923 @default.
- W2779137890 cites W2106350386 @default.
- W2779137890 cites W2108609202 @default.
- W2779137890 cites W2113563738 @default.
- W2779137890 cites W2115350520 @default.
- W2779137890 cites W2116242713 @default.
- W2779137890 cites W2122442595 @default.
- W2779137890 cites W2125093925 @default.
- W2779137890 cites W2127400392 @default.
- W2779137890 cites W2130858725 @default.
- W2779137890 cites W2145438380 @default.
- W2779137890 cites W2150362274 @default.
- W2779137890 cites W2152130168 @default.
- W2779137890 cites W2153802700 @default.
- W2779137890 cites W2156841776 @default.
- W2779137890 cites W2157626642 @default.
- W2779137890 cites W2157863718 @default.
- W2779137890 cites W2158287682 @default.
- W2779137890 cites W2162053770 @default.
- W2779137890 cites W2166094499 @default.
- W2779137890 cites W2200771681 @default.
- W2779137890 cites W2229935667 @default.
- W2779137890 cites W2286296536 @default.
- W2779137890 cites W231724911 @default.
- W2779137890 cites W2339988748 @default.
- W2779137890 cites W2346011598 @default.
- W2779137890 cites W2403062699 @default.
- W2779137890 cites W2509314641 @default.
- W2779137890 cites W2531209815 @default.
- W2779137890 cites W2551718479 @default.
- W2779137890 cites W2580439088 @default.
- W2779137890 cites W2583326055 @default.
- W2779137890 cites W2587683955 @default.
- W2779137890 cites W2592270240 @default.
- W2779137890 cites W2595812558 @default.
- W2779137890 cites W2596580804 @default.
- W2779137890 cites W2599244189 @default.
- W2779137890 cites W2615840631 @default.
- W2779137890 cites W2623245238 @default.
- W2779137890 cites W2709595243 @default.
- W2779137890 cites W2736745879 @default.
- W2779137890 cites W2736913445 @default.
- W2779137890 cites W2746574162 @default.
- W2779137890 cites W2747104396 @default.
- W2779137890 cites W2753034449 @default.
- W2779137890 cites W4242844295 @default.
- W2779137890 cites W59912805 @default.
- W2779137890 cites W645253406 @default.