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- W2779404860 abstract "Using the Isle of Wight Birth Cohort (IOWBC) we sought to understand the prevalence and characteristics of atopic disease in young adults. Method: The IOWBC was established in 1989 on the Isle of Wight, UK. It recruited all children from consenting parents born in that year on the Island (n= 1456). Presence of wheeze, allergic co-morbidities and risk factors were assessed and data collected at birth, 1, 2, 4, 10, 18 and 26-years. Results: 1033 (70.9%) members participated in the 26-year follow-up. Of these, 556 underwent skin prick testing and 45.7% (254) demonstrated atopic sensitisation. This compared to 19.7% at 4, 26.9% at 10 and 41.3% at 18 years. Males (51.2% (124)) were more likely to be atopic than females (40.9% (130) p=0.009). They were more likely to be allergic to house dust mite (37.8% (90) vs 28.3% (90), p=0.018), grass (32.4% (77) vs (22.0%) (70) p=0.006), tree (8.4% (20) vs 2.8% (9) p=0.003), dog (12.6% (30) vs 6.0% (19) p=0.006) and peanut (5.9% (14) vs 2.2% (7) p=0.024). Those currently wheezing were also more likely to be atopic (60.7% (88) vs 40.4% (166) p Conclusion: Atopic sensitisation increases across childhood and into young adulthood. At 26 years atopy is more prevalent in males. Atopy (particularly to aeroallergens) is also associated with current wheeze at 26." @default.
- W2779404860 created "2018-01-05" @default.
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- W2779404860 date "2017-09-01" @default.
- W2779404860 modified "2023-09-23" @default.
- W2779404860 title "Atopic Sensitisation of the Isle of Wight Birth Cohort at 26 Years" @default.
- W2779404860 doi "https://doi.org/10.1183/1393003.congress-2017.pa4049" @default.
- W2779404860 hasPublicationYear "2017" @default.
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