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- W2779798924 abstract "Objective: To Describe Infectious Intracranial Aneurysm(IIA) in Infective Endocarditis(IE) Background: IIA can complicate IE. We aim to describe the characteristics of IIA and assess indications for cerebral angiography. Design/Methods: We reviewed IIAs among 116 consecutive active IE by Duke’s criteria with neurological consultation or admission to stroke neurology service in a tertiary referral center from January 2015 to July 2016. Susceptibility weighted imaging(SWI) hemorrhage was defined as low signal on SWI in sulci or parenchyma that was not apparent on CT. Results: Of 116 patients, 74 persons(63.8%, mean age 54) underwent digital subtraction angiography(DSA). IIAs were identified in 13(17.6%). All of 13 IIAs were unruptured and only one IIA had unrelated intracranial hemorrhage on CT. None of the IIA was seen with CTA or MRA. Eleven(85%) IIAs had clinical strokes(10 ischemic strokes, 1 intracerebral hemorrhage, median NIH 3), and 2 neurologically asymptomatic with abnormal MRI. Six of 9 IIAs had SWI hemorrhage in sulci or parenchyma(5 in sulci, 5 in parenchyma, and 1 in both) and all of the lesions were in the vicinity of IIA. Contrast MRI was performed in 7 IIAs, and 4 had enhancements, all of which were present near the location of IIAs. Ischemic stroke, intracranial hemorrhage, intravenous drug abuse, and type of valve were not associated with the presence of IIA. Three patients remained on antibiotic alone, 5 had antibiotic with coil embolization, and, 5 had antibiotic with glue embolization. Ten patients with IIAs had valvular surgery, including one with untreated IIA. Out of all, only one intracerebral hemorrhage occurred as perioperative complication unrelated to treated IIA. Conclusions: IIAs were found in approximately one fifth of IE persons who underwent DSA. Imaging characteristics such as SWI hemorrhage in sulci or parenchyma and contrast enhancement appear to correlate with the presence of IIA. DSA should be performed when they are present. Disclosure: Dr. Cho has nothing to disclose. Dr. Marquardt has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. Thatikunta has nothing to disclose. Dr. Uchino has nothing to disclose. Dr. Wisco has nothing to disclose." @default.
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- W2779798924 date "2017-04-18" @default.
- W2779798924 modified "2023-09-23" @default.
- W2779798924 title "The Characteristics of Infectious Intracranial Aneurysm and Indication of Cerebral Angiogram in Infective Endocarditis (P2.296)" @default.
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