FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2779897836> ?p ?o ?g. }

• W2779897836 endingPage "390" @default.
• W2779897836 startingPage "380" @default.
• W2779897836 abstract "Photonics, especially optical coherence elastography (OCE) and second harmonic generation (SHG) imaging are novel high-resolution imaging modalities for characterization of biological tissues. Following our preliminary experience, we hypothesized that OCE and SHG imaging would delineate the microstructure of prostate tissue and aid in distinguishing cancer from the normal benign prostatic tissue. Furthermore, these approaches may assist in characterization of the grade of cancer, as well. In this study, we confirmed a high diagnostic accuracy of OCE and SHG imaging in the detection and characterization of prostate cancer for a large set of biopsy tissues obtained from men suspected to have prostate cancer using transrectal ultrasound (TRUS). The two techniques and methods described here are complementary, one depicts the stiffness of tissues and the other illustrates the orientation of collagen structure around the cancerous lesions. The results showed that stiffness of cancer tissue was ~57.63% higher than that of benign tissue (Young's modulus of 698.43±125.29 kPa for cancerous tissue vs 443.07±88.95 kPa for benign tissue with OCE. Using histology as a reference standard and 600 kPa as a cut-off threshold, the data analysis showed sensitivity and specificity of 89.6 and 99.8%, respectively. Corresponding positive and negative predictive values were 99.5 and 94.6%, respectively. There was a significant difference noticed in terms of Young's modulus for different Gleason scores estimated by OCE (P-value<0.05). For SHG, distinct patterns of collagen distribution were seen for different Gleason grade disease with computed quantification employing a ratio of anisotropic to isotropic (A:I ratio) and this correlated with disease aggressiveness." @default.
• W2779897836 created "2018-01-05" @default.
• W2779897836 creator A5001194841 @default.
• W2779897836 creator A5010782578 @default.
• W2779897836 creator A5037180023 @default.
• W2779897836 creator A5050919579 @default.
• W2779897836 creator A5053386502 @default.
• W2779897836 creator A5057320824 @default.
• W2779897836 creator A5077829104 @default.
• W2779897836 creator A5083133315 @default.
• W2779897836 creator A5084717091 @default.
• W2779897836 date "2018-03-01" @default.
• W2779897836 modified "2023-10-01" @default.
• W2779897836 title "Microscale characterization of prostate biopsies tissues using optical coherence elastography and second harmonic generation imaging" @default.
• W2779897836 cites W1582403569 @default.
• W2779897836 cites W1966187746 @default.
• W2779897836 cites W1966571077 @default.
• W2779897836 cites W1976862087 @default.
• W2779897836 cites W1987695988 @default.
• W2779897836 cites W1991370659 @default.
• W2779897836 cites W1992838105 @default.
• W2779897836 cites W2001404199 @default.
• W2779897836 cites W2010292060 @default.
• W2779897836 cites W2018371450 @default.
• W2779897836 cites W2028910503 @default.
• W2779897836 cites W2035721564 @default.
• W2779897836 cites W2036985568 @default.
• W2779897836 cites W2052868878 @default.
• W2779897836 cites W2056254464 @default.
• W2779897836 cites W2062424181 @default.
• W2779897836 cites W2069189999 @default.
• W2779897836 cites W2071027495 @default.
• W2779897836 cites W2073019566 @default.
• W2779897836 cites W2074595488 @default.
• W2779897836 cites W2101658644 @default.
• W2779897836 cites W2101728107 @default.
• W2779897836 cites W2104479723 @default.
• W2779897836 cites W2114022098 @default.
• W2779897836 cites W2117345577 @default.
• W2779897836 cites W2131834580 @default.
• W2779897836 cites W2145305918 @default.
• W2779897836 cites W2147407583 @default.
• W2779897836 cites W2152056274 @default.
• W2779897836 cites W2168033859 @default.
• W2779897836 cites W2168833460 @default.
• W2779897836 cites W2276086050 @default.
• W2779897836 cites W2408581215 @default.
• W2779897836 cites W2508744997 @default.
• W2779897836 cites W2605659401 @default.
• W2779897836 cites W4249064981 @default.
• W2779897836 doi "https://doi.org/10.1038/labinvest.2017.132" @default.
• W2779897836 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5842892" @default.
• W2779897836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29251735" @default.
• W2779897836 hasPublicationYear "2018" @default.
• W2779897836 type Work @default.
• W2779897836 sameAs 2779897836 @default.
• W2779897836 citedByCount "19" @default.
• W2779897836 countsByYear W27798978362018 @default.
• W2779897836 countsByYear W27798978362019 @default.
• W2779897836 countsByYear W27798978362020 @default.
• W2779897836 countsByYear W27798978362021 @default.
• W2779897836 countsByYear W27798978362022 @default.
• W2779897836 countsByYear W27798978362023 @default.
• W2779897836 crossrefType "journal-article" @default.
• W2779897836 hasAuthorship W2779897836A5001194841 @default.
• W2779897836 hasAuthorship W2779897836A5010782578 @default.
• W2779897836 hasAuthorship W2779897836A5037180023 @default.
• W2779897836 hasAuthorship W2779897836A5050919579 @default.
• W2779897836 hasAuthorship W2779897836A5053386502 @default.
• W2779897836 hasAuthorship W2779897836A5057320824 @default.
• W2779897836 hasAuthorship W2779897836A5077829104 @default.
• W2779897836 hasAuthorship W2779897836A5083133315 @default.
• W2779897836 hasAuthorship W2779897836A5084717091 @default.
• W2779897836 hasBestOaLocation W27798978361 @default.
• W2779897836 hasConcept C120665830 @default.
• W2779897836 hasConcept C121332964 @default.
• W2779897836 hasConcept C121608353 @default.
• W2779897836 hasConcept C126322002 @default.
• W2779897836 hasConcept C126838900 @default.
• W2779897836 hasConcept C136229726 @default.
• W2779897836 hasConcept C142724271 @default.
• W2779897836 hasConcept C143753070 @default.
• W2779897836 hasConcept C192562407 @default.
• W2779897836 hasConcept C2775934546 @default.
• W2779897836 hasConcept C2776235491 @default.
• W2779897836 hasConcept C2777690781 @default.
• W2779897836 hasConcept C2778818243 @default.
• W2779897836 hasConcept C2780192828 @default.
• W2779897836 hasConcept C30713254 @default.
• W2779897836 hasConcept C31601959 @default.
• W2779897836 hasConcept C520434653 @default.
• W2779897836 hasConcept C71924100 @default.
• W2779897836 hasConceptScore W2779897836C120665830 @default.
• W2779897836 hasConceptScore W2779897836C121332964 @default.
• W2779897836 hasConceptScore W2779897836C121608353 @default.
• W2779897836 hasConceptScore W2779897836C126322002 @default.
• W2779897836 hasConceptScore W2779897836C126838900 @default.
• W2779897836 hasConceptScore W2779897836C136229726 @default.

• next