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- W2780453723 endingPage "406" @default.
- W2780453723 startingPage "398" @default.
- W2780453723 abstract "In recent years, lipid-coated calcium-phosphate (LCP) nanoparticle has been developed as a versatile platform for delivery of various therapeutics including gene, protein/peptide, chemotherapeutics and theranostic agents. The high endosomal escape, coupled with the ability to efficiently encapsulate phosphorylated drugs or prodrugs, make LCP become attractive vehicle for drug delivery. Additionally, the principle behind LCP formulation has also allowed rational design of LCP-derived nanoparticles (NPs) with other solid core or lipid membrane to overcome the various drug delivery barriers. Here, we briefly review the history of the development of LCP NPs, highlight the optimisations and modulations in the development process, and summarise the major applications of LCP NPs and LCP-derived NPs in drug delivery." @default.
- W2780453723 created "2018-01-05" @default.
- W2780453723 creator A5002855077 @default.
- W2780453723 creator A5076644434 @default.
- W2780453723 creator A5088958812 @default.
- W2780453723 date "2017-12-27" @default.
- W2780453723 modified "2023-10-15" @default.
- W2780453723 title "Lipid-coated calcium phosphate nanoparticle and beyond: a versatile platform for drug delivery" @default.
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- W2780453723 doi "https://doi.org/10.1080/1061186x.2017.1419360" @default.
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- W2780453723 hasPublicationYear "2017" @default.
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