FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2780491695> ?p ?o ?g. }

• W2780491695 endingPage "174" @default.
• W2780491695 startingPage "165" @default.
• W2780491695 abstract "Some studies suggest that chronic low-grade inflammation is involved in insulin resistance in polycystic ovary syndrome (PCOS). This study assessed possible involvement of alteration in expression of two pro-inflammatory factors, tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in adipose tissues of PCOS rats in the impairment of insulin actions. Also, effects of resveratrol as an anti-inflammatory agent were investigated.Fifteen female Wistar rats (21 days old) were divided into three groups (n=5): I) Control, II) PCO-model-saline: served as PCOS rats and to induce PCOS, received subcutaneously testosterone enanthate 1 mg/100 g body weight subcutaneously for 35 days, III) PCO-model-resveratrol, after receiving testosterone, received resveratrol 10 mg/kg intraperitoneally for 28 days. The expression of Tnf-α and Il-6 mRNAs in adipose tissues was determined by the qRT-PCR method.The Il-6 mRNA expression in the visceral adipose tissue of PCOS rats was increased in comparison to controls (P<0.05). Tnf-α and Il-6 mRNA expression in visceral and subcutaneous adipose tissues of polycystic ovarian rats was similar to controls. The expression of Tnf-α mRNA in subcutaneous adipose tissue and Tnf-α and Il-6 mRNAs in the visceral adipose tissue of the PCO-model-resveratrol group were lower than PCOS rats (P<0.05).Increased expression of Il-6 mRNA in the visceral adipose tissue of polycystic ovarian rats may be one cause of insulin resistance observed in them and resveratrol as an anti-inflammatory and anti-hyperglycemic agent may decrease the risk of diabetes by reduction of expression of pro-inflammatory cytokines TNF-α and IL-6 in PCOS patients." @default.
• W2780491695 created "2018-01-05" @default.
• W2780491695 creator A5001122221 @default.
• W2780491695 creator A5027247591 @default.
• W2780491695 creator A5049651989 @default.
• W2780491695 date "2018-02-01" @default.
• W2780491695 modified "2023-09-23" @default.
• W2780491695 title "Evaluation of TNF-α and IL-6 mRNAs expressions in visceral and subcutaneous adipose tissues of polycystic ovarian rats and effects of resveratrol." @default.
• W2780491695 cites W1523909433 @default.
• W2780491695 cites W1558113022 @default.
• W2780491695 cites W1570362997 @default.
• W2780491695 cites W1589544052 @default.
• W2780491695 cites W1821296103 @default.
• W2780491695 cites W1888335775 @default.
• W2780491695 cites W1968873480 @default.
• W2780491695 cites W1971865201 @default.
• W2780491695 cites W1972171824 @default.
• W2780491695 cites W1973239749 @default.
• W2780491695 cites W1975183982 @default.
• W2780491695 cites W1978168113 @default.
• W2780491695 cites W1979903467 @default.
• W2780491695 cites W1986962958 @default.
• W2780491695 cites W2013466700 @default.
• W2780491695 cites W2016610386 @default.
• W2780491695 cites W2020468088 @default.
• W2780491695 cites W2024992877 @default.
• W2780491695 cites W2028242557 @default.
• W2780491695 cites W2031695379 @default.
• W2780491695 cites W2038553345 @default.
• W2780491695 cites W2040783439 @default.
• W2780491695 cites W2041130899 @default.
• W2780491695 cites W2042639777 @default.
• W2780491695 cites W2043106623 @default.
• W2780491695 cites W2045508343 @default.
• W2780491695 cites W2049979037 @default.
• W2780491695 cites W2053105417 @default.
• W2780491695 cites W2056964280 @default.
• W2780491695 cites W2058178280 @default.
• W2780491695 cites W2063057213 @default.
• W2780491695 cites W2067082722 @default.
• W2780491695 cites W2080114261 @default.
• W2780491695 cites W2089269477 @default.
• W2780491695 cites W2093404210 @default.
• W2780491695 cites W2096682790 @default.
• W2780491695 cites W2097740790 @default.
• W2780491695 cites W2099581857 @default.
• W2780491695 cites W2100211815 @default.
• W2780491695 cites W2107010539 @default.
• W2780491695 cites W2114570899 @default.
• W2780491695 cites W2117499294 @default.
• W2780491695 cites W2119399665 @default.
• W2780491695 cites W2129316761 @default.
• W2780491695 cites W2130850001 @default.
• W2780491695 cites W2146845495 @default.
• W2780491695 cites W2154587590 @default.
• W2780491695 cites W2167226448 @default.
• W2780491695 cites W2167634393 @default.
• W2780491695 cites W2170051958 @default.
• W2780491695 cites W2171067844 @default.
• W2780491695 cites W2175474731 @default.
• W2780491695 cites W2186218348 @default.
• W2780491695 cites W2331176038 @default.
• W2780491695 doi "https://doi.org/10.22038/ijbms.2017.24801.6167" @default.
• W2780491695 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5811755" @default.
• W2780491695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29456813" @default.
• W2780491695 hasPublicationYear "2018" @default.
• W2780491695 type Work @default.
• W2780491695 sameAs 2780491695 @default.
• W2780491695 citedByCount "19" @default.
• W2780491695 countsByYear W27804916952019 @default.
• W2780491695 countsByYear W27804916952020 @default.
• W2780491695 countsByYear W27804916952021 @default.
• W2780491695 countsByYear W27804916952022 @default.
• W2780491695 countsByYear W27804916952023 @default.
• W2780491695 crossrefType "journal-article" @default.
• W2780491695 hasAuthorship W2780491695A5001122221 @default.
• W2780491695 hasAuthorship W2780491695A5027247591 @default.
• W2780491695 hasAuthorship W2780491695A5049651989 @default.
• W2780491695 hasConcept C126322002 @default.
• W2780491695 hasConcept C134018914 @default.
• W2780491695 hasConcept C171089720 @default.
• W2780491695 hasConcept C17991360 @default.
• W2780491695 hasConcept C2776816829 @default.
• W2780491695 hasConcept C2776914184 @default.
• W2780491695 hasConcept C2777391703 @default.
• W2780491695 hasConcept C2777397205 @default.
• W2780491695 hasConcept C2779279991 @default.
• W2780491695 hasConcept C2779306644 @default.
• W2780491695 hasConcept C3018442814 @default.
• W2780491695 hasConcept C71924100 @default.
• W2780491695 hasConcept C98274493 @default.
• W2780491695 hasConceptScore W2780491695C126322002 @default.
• W2780491695 hasConceptScore W2780491695C134018914 @default.
• W2780491695 hasConceptScore W2780491695C171089720 @default.
• W2780491695 hasConceptScore W2780491695C17991360 @default.
• W2780491695 hasConceptScore W2780491695C2776816829 @default.
• W2780491695 hasConceptScore W2780491695C2776914184 @default.
• W2780491695 hasConceptScore W2780491695C2777391703 @default.

• next