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- W2780967529 endingPage "2359" @default.
- W2780967529 startingPage "2359" @default.
- W2780967529 abstract "Yeonsan Ogye is a rare Korean domestic chicken breed whose entire body, including feathers and skin, has a unique black coloring. Although some protein-coding genes related to this unique feature have been examined, non-coding elements have not been widely investigated. Thus, we evaluated coding and non-coding transcriptome expression and identified long non-coding RNAs functionally linked to protein-coding genes in Ogye. High-throughput RNA sequencing and DNA methylation sequencing were performed to profile the expression of 14,264 Ogye protein-coding and 6900 long non-coding RNA (lncRNA) genes and detect DNA methylation in 20 different tissues of an individual Ogye. Approximately 75% of Ogye lncRNAs and 45% of protein-coding genes showed tissue-specific expression. For some genes, tissue-specific expression levels were inversely correlated with DNA methylation levels in their promoters. Approximately 39% of tissue-specific lncRNAs displayed functional associations with proximal or distal protein-coding genes. Heat shock transcription factor 2-associated lncRNAs appeared to be functionally linked to protein-coding genes specifically expressed in black skin tissues, more syntenically conserved in mammals, and differentially expressed in black relative to in white tissues. Pending experimental validation, our findings increase the understanding of how the non-coding genome regulates unique phenotypes and can be used for future genomic breeding of chickens." @default.
- W2780967529 created "2018-01-05" @default.
- W2780967529 creator A5000219929 @default.
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- W2780967529 date "2018-08-10" @default.
- W2780967529 modified "2023-10-15" @default.
- W2780967529 title "Non-Coding Transcriptome Maps across Twenty Tissues of the Korean Black Chicken, Yeonsan Ogye" @default.
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- W2780967529 cites W1843014747 @default.
- W2780967529 cites W1972440741 @default.
- W2780967529 cites W1972717887 @default.
- W2780967529 cites W1974690690 @default.
- W2780967529 cites W1977943782 @default.
- W2780967529 cites W1978901723 @default.
- W2780967529 cites W1985570666 @default.
- W2780967529 cites W1987047126 @default.
- W2780967529 cites W1994745633 @default.
- W2780967529 cites W1996060670 @default.
- W2780967529 cites W1998075825 @default.
- W2780967529 cites W1999746344 @default.
- W2780967529 cites W2002364516 @default.
- W2780967529 cites W2006597186 @default.
- W2780967529 cites W2014787267 @default.
- W2780967529 cites W2017844161 @default.
- W2780967529 cites W2028434128 @default.
- W2780967529 cites W2029919331 @default.
- W2780967529 cites W2046684403 @default.
- W2780967529 cites W2049905357 @default.
- W2780967529 cites W2053293102 @default.
- W2780967529 cites W2054286018 @default.
- W2780967529 cites W2055505035 @default.
- W2780967529 cites W2058615001 @default.
- W2780967529 cites W2060390444 @default.
- W2780967529 cites W2068205741 @default.
- W2780967529 cites W2073819457 @default.
- W2780967529 cites W2075810753 @default.
- W2780967529 cites W2078993607 @default.
- W2780967529 cites W2085971867 @default.
- W2780967529 cites W2088017477 @default.
- W2780967529 cites W2091161969 @default.
- W2780967529 cites W2098425296 @default.
- W2780967529 cites W2103777723 @default.
- W2780967529 cites W2105462242 @default.
- W2780967529 cites W2106678197 @default.
- W2780967529 cites W2108366237 @default.
- W2780967529 cites W2108672729 @default.
- W2780967529 cites W2120597842 @default.
- W2780967529 cites W2121828161 @default.
- W2780967529 cites W2123973342 @default.
- W2780967529 cites W2124985265 @default.
- W2780967529 cites W2129078669 @default.
- W2780967529 cites W2130313087 @default.
- W2780967529 cites W2131374955 @default.
- W2780967529 cites W2134033103 @default.
- W2780967529 cites W2134526812 @default.
- W2780967529 cites W2139347946 @default.
- W2780967529 cites W2139535521 @default.
- W2780967529 cites W2141831115 @default.
- W2780967529 cites W2142019735 @default.
- W2780967529 cites W2148464879 @default.
- W2780967529 cites W2152239989 @default.
- W2780967529 cites W2153268494 @default.
- W2780967529 cites W2156392314 @default.
- W2780967529 cites W2156880688 @default.
- W2780967529 cites W2157952888 @default.
- W2780967529 cites W2158217645 @default.
- W2780967529 cites W2158866358 @default.
- W2780967529 cites W2160333540 @default.
- W2780967529 cites W2161901690 @default.
- W2780967529 cites W2163340789 @default.
- W2780967529 cites W2166810745 @default.
- W2780967529 cites W2169456326 @default.
- W2780967529 cites W2174181728 @default.
- W2780967529 cites W2198153867 @default.
- W2780967529 cites W2245239316 @default.
- W2780967529 cites W2256359187 @default.
- W2780967529 cites W2286751485 @default.
- W2780967529 cites W2295037017 @default.
- W2780967529 cites W2338430470 @default.
- W2780967529 cites W2366276793 @default.
- W2780967529 cites W2418974633 @default.
- W2780967529 cites W2485289953 @default.
- W2780967529 cites W2586079296 @default.
- W2780967529 cites W2605153855 @default.
- W2780967529 cites W2773326374 @default.
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- W2780967529 doi "https://doi.org/10.3390/ijms19082359" @default.
- W2780967529 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6121550" @default.
- W2780967529 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30103450" @default.
- W2780967529 hasPublicationYear "2018" @default.
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