FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2781309981> ?p ?o ?g. }

• W2781309981 endingPage "97" @default.
• W2781309981 startingPage "89" @default.
• W2781309981 abstract "The correlation between O-6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation and esophageal cancer remains controversial. This study was conducted to evaluate the clinical effect of MGMT promoter methylation on esophageal carcinoma patients.A literature search was conducted in the PubMed, EMBASE, EBSCO, and Cochrane Library databases. The overall OR and corresponding 95% CI were calculated using the random-effects model.Finally, 17 eligible studies were identified in this meta-analysis; these studies included a total of 1,368 patients with esophageal carcinoma and 1,489 with nonmalignant controls. MGMT promoter methylation was significantly higher in esophageal carcinoma tissue samples than in nonmalignant tissue samples (OR 3.64, p < 0.001). Promoter methylation of the MGMT gene was not associated with gender, cigarette smoking, drinking behavior, or tumor differentiation, but MGMT promoter methylation was correlated with age (≥60 vs. <60 years: OR 1.64, p = 0.028), lymph node status (positive status vs. negative status: OR 2.39, p = 0.024), and clinical stage (stages 3-4 vs. 1-2: OR 10.59, p < 0.001).Our findings suggest that MGMT promoter methylation may be correlated with esophageal cancer carcinogenesis and could be associated with age, lymph node status, and clinical stage." @default.
• W2781309981 created "2018-01-05" @default.
• W2781309981 creator A5020720409 @default.
• W2781309981 creator A5087980866 @default.
• W2781309981 date "2017-12-20" @default.
• W2781309981 modified "2023-09-26" @default.
• W2781309981 title "Clinical Significance of O-6-Methylguanine-DNA-Methyltransferase Promoter Methylation in Patients with Esophageal Carcinoma: A Systematic Meta-Analysis" @default.
• W2781309981 cites W1710102054 @default.
• W2781309981 cites W1965262464 @default.
• W2781309981 cites W1969704595 @default.
• W2781309981 cites W1974625504 @default.
• W2781309981 cites W1978217612 @default.
• W2781309981 cites W1982118330 @default.
• W2781309981 cites W1982228885 @default.
• W2781309981 cites W2020830322 @default.
• W2781309981 cites W2022631493 @default.
• W2781309981 cites W2023666414 @default.
• W2781309981 cites W2038222027 @default.
• W2781309981 cites W2043966181 @default.
• W2781309981 cites W2072994151 @default.
• W2781309981 cites W2076877577 @default.
• W2781309981 cites W2082561902 @default.
• W2781309981 cites W2086492013 @default.
• W2781309981 cites W2096576375 @default.
• W2781309981 cites W2112222750 @default.
• W2781309981 cites W2117809535 @default.
• W2781309981 cites W2119502157 @default.
• W2781309981 cites W2122120224 @default.
• W2781309981 cites W2125435699 @default.
• W2781309981 cites W2130396542 @default.
• W2781309981 cites W2138703169 @default.
• W2781309981 cites W2140525070 @default.
• W2781309981 cites W2141976921 @default.
• W2781309981 cites W2147977885 @default.
• W2781309981 cites W2157823046 @default.
• W2781309981 cites W2161052244 @default.
• W2781309981 cites W2162421937 @default.
• W2781309981 cites W2167325961 @default.
• W2781309981 cites W2168775120 @default.
• W2781309981 cites W2254685106 @default.
• W2781309981 cites W2266011888 @default.
• W2781309981 cites W2278556189 @default.
• W2781309981 cites W2314540303 @default.
• W2781309981 cites W2419582531 @default.
• W2781309981 cites W2483690177 @default.
• W2781309981 cites W2520647351 @default.
• W2781309981 cites W2538351047 @default.
• W2781309981 cites W2567123034 @default.
• W2781309981 cites W2580454666 @default.
• W2781309981 cites W2601686349 @default.
• W2781309981 doi "https://doi.org/10.1159/000481342" @default.
• W2781309981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29258097" @default.
• W2781309981 hasPublicationYear "2017" @default.
• W2781309981 type Work @default.
• W2781309981 sameAs 2781309981 @default.
• W2781309981 citedByCount "5" @default.
• W2781309981 countsByYear W27813099812019 @default.
• W2781309981 countsByYear W27813099812020 @default.
• W2781309981 countsByYear W27813099812023 @default.
• W2781309981 crossrefType "journal-article" @default.
• W2781309981 hasAuthorship W2781309981A5020720409 @default.
• W2781309981 hasAuthorship W2781309981A5087980866 @default.
• W2781309981 hasConcept C104317684 @default.
• W2781309981 hasConcept C121608353 @default.
• W2781309981 hasConcept C126322002 @default.
• W2781309981 hasConcept C143998085 @default.
• W2781309981 hasConcept C146357865 @default.
• W2781309981 hasConcept C150194340 @default.
• W2781309981 hasConcept C151730666 @default.
• W2781309981 hasConcept C190727270 @default.
• W2781309981 hasConcept C2776478404 @default.
• W2781309981 hasConcept C2777546739 @default.
• W2781309981 hasConcept C2779742542 @default.
• W2781309981 hasConcept C33288867 @default.
• W2781309981 hasConcept C502942594 @default.
• W2781309981 hasConcept C54355233 @default.
• W2781309981 hasConcept C555283112 @default.
• W2781309981 hasConcept C63363279 @default.
• W2781309981 hasConcept C71924100 @default.
• W2781309981 hasConcept C86803240 @default.
• W2781309981 hasConcept C91965660 @default.
• W2781309981 hasConcept C95190672 @default.
• W2781309981 hasConceptScore W2781309981C104317684 @default.
• W2781309981 hasConceptScore W2781309981C121608353 @default.
• W2781309981 hasConceptScore W2781309981C126322002 @default.
• W2781309981 hasConceptScore W2781309981C143998085 @default.
• W2781309981 hasConceptScore W2781309981C146357865 @default.
• W2781309981 hasConceptScore W2781309981C150194340 @default.
• W2781309981 hasConceptScore W2781309981C151730666 @default.
• W2781309981 hasConceptScore W2781309981C190727270 @default.
• W2781309981 hasConceptScore W2781309981C2776478404 @default.
• W2781309981 hasConceptScore W2781309981C2777546739 @default.
• W2781309981 hasConceptScore W2781309981C2779742542 @default.
• W2781309981 hasConceptScore W2781309981C33288867 @default.
• W2781309981 hasConceptScore W2781309981C502942594 @default.
• W2781309981 hasConceptScore W2781309981C54355233 @default.
• W2781309981 hasConceptScore W2781309981C555283112 @default.
• W2781309981 hasConceptScore W2781309981C63363279 @default.

• next