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- W2781370437 abstract "Our understanding of breast cancer and its therapeutic approach has improved greatly due to the advancement of molecular biology in recent years. Clinically, breast cancers are characterized into three basic types based on their immunohistochemical properties. They are triple-negative breast cancer, estrogen receptor (ER) and progesterone receptor (PR)-positive-HR positive breast cancer, and human epidermal growth factor receptor 2 (HER2)-positive breast cancer. Even though these subtypes have been characterized, assessment of a breast cancer's receptor status is still widely used to determine whether or not a targeted therapy could be applied. Moreover, drug resistance is common in all breast cancer types despite the different treatment modalities applied. The development of resistance to different therapeutics is not mutually exclusive. It seems that tumor could be resistant to multiple treatment strategies, such as being both chemoresistant and monoclonal antibody resistant. However, the underlying mechanisms are complicated and need further investigation. In this chapter, we aim to provide a brief review of the different types of breast cancer and their respective treatment strategies. We also review the possible mechanisms of potential drug resistance associated with each treatment type. We believe that a better understanding of the drug resistance mechanisms can lead to a more effective and efficient therapeutic success." @default.
- W2781370437 created "2018-01-05" @default.
- W2781370437 creator A5028386044 @default.
- W2781370437 creator A5078136185 @default.
- W2781370437 creator A5089771725 @default.
- W2781370437 date "2017-01-01" @default.
- W2781370437 modified "2023-10-14" @default.
- W2781370437 title "Predicting and Overcoming Chemotherapeutic Resistance in Breast Cancer" @default.
- W2781370437 cites W1273429064 @default.
- W2781370437 cites W1534171442 @default.
- W2781370437 cites W1576432682 @default.
- W2781370437 cites W1597483432 @default.
- W2781370437 cites W1644299043 @default.
- W2781370437 cites W1719665247 @default.
- W2781370437 cites W1791762728 @default.
- W2781370437 cites W1822510418 @default.
- W2781370437 cites W1847015339 @default.
- W2781370437 cites W1857266517 @default.
- W2781370437 cites W1872518637 @default.
- W2781370437 cites W1880891411 @default.
- W2781370437 cites W1927418190 @default.
- W2781370437 cites W1931183350 @default.
- W2781370437 cites W1966937303 @default.
- W2781370437 cites W1968602934 @default.
- W2781370437 cites W1969346276 @default.
- W2781370437 cites W1970136142 @default.
- W2781370437 cites W1970208153 @default.
- W2781370437 cites W1970755773 @default.
- W2781370437 cites W1972841107 @default.
- W2781370437 cites W1974504182 @default.
- W2781370437 cites W1975570973 @default.
- W2781370437 cites W1979946545 @default.
- W2781370437 cites W1980538880 @default.
- W2781370437 cites W1982957001 @default.
- W2781370437 cites W1986471913 @default.
- W2781370437 cites W1987323012 @default.
- W2781370437 cites W1987337616 @default.
- W2781370437 cites W1987362747 @default.
- W2781370437 cites W1987642949 @default.
- W2781370437 cites W1988462970 @default.
- W2781370437 cites W1988548899 @default.
- W2781370437 cites W1993322072 @default.
- W2781370437 cites W1993452864 @default.
- W2781370437 cites W1995075648 @default.
- W2781370437 cites W1995224853 @default.
- W2781370437 cites W1996931025 @default.
- W2781370437 cites W1997055587 @default.
- W2781370437 cites W1999022874 @default.
- W2781370437 cites W1999653222 @default.
- W2781370437 cites W2002013266 @default.
- W2781370437 cites W2004757762 @default.
- W2781370437 cites W2004881066 @default.
- W2781370437 cites W2004946118 @default.
- W2781370437 cites W2005547107 @default.
- W2781370437 cites W2005895632 @default.
- W2781370437 cites W2006778039 @default.
- W2781370437 cites W2007040134 @default.
- W2781370437 cites W2007073167 @default.
- W2781370437 cites W2007196889 @default.
- W2781370437 cites W2007916488 @default.
- W2781370437 cites W2009098155 @default.
- W2781370437 cites W2012116166 @default.
- W2781370437 cites W2012505736 @default.
- W2781370437 cites W2013822060 @default.
- W2781370437 cites W2013956549 @default.
- W2781370437 cites W2014599726 @default.
- W2781370437 cites W2015360671 @default.
- W2781370437 cites W2016429826 @default.
- W2781370437 cites W2018105469 @default.
- W2781370437 cites W2018939316 @default.
- W2781370437 cites W2019355348 @default.
- W2781370437 cites W2020224707 @default.
- W2781370437 cites W2020697195 @default.
- W2781370437 cites W2021583504 @default.
- W2781370437 cites W2021654438 @default.
- W2781370437 cites W2022006860 @default.
- W2781370437 cites W2022102157 @default.
- W2781370437 cites W2023297465 @default.
- W2781370437 cites W2023720844 @default.
- W2781370437 cites W2023755204 @default.
- W2781370437 cites W2023826235 @default.
- W2781370437 cites W2027684043 @default.
- W2781370437 cites W2029938510 @default.
- W2781370437 cites W2030566540 @default.
- W2781370437 cites W2031018710 @default.
- W2781370437 cites W2031915537 @default.
- W2781370437 cites W2032037224 @default.
- W2781370437 cites W2033044241 @default.
- W2781370437 cites W2033278321 @default.
- W2781370437 cites W2035880310 @default.
- W2781370437 cites W2040685978 @default.
- W2781370437 cites W2041617023 @default.
- W2781370437 cites W2042602698 @default.
- W2781370437 cites W2042619042 @default.
- W2781370437 cites W2043506695 @default.
- W2781370437 cites W2044085368 @default.
- W2781370437 cites W2044222436 @default.
- W2781370437 cites W2045286167 @default.