Matches in SemOpenAlex for { <https://semopenalex.org/work/W2781542011> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2781542011 endingPage "424" @default.
- W2781542011 startingPage "424" @default.
- W2781542011 abstract "Background: Despite the evolution of Ventricular Assist Devices (VADs), VAD patients still suffer from complications, often due to damage to the blood components by fluid dynamic stress. Damage to the leukocytes may contribute to infections, one of the biggest post-surgical problems. In experiments destruction of leukocytes was found to depend on impeller speed, flow rate and the type of leukocyte. Aim: The aim was to develop a numerical model for leukocyte deformation to help explain differences in damage levels between VAD operating conditions and between different cell types. Methods: The cell was modelled as a spherical compound liquid drop with concentric nucleus. The Navier- Stokes equations were solved using the finite volume code OpenFOAM, with a Volume of Fluid method to calculate fluid volume fractions. The surface tension of the fluids represented the membranes. The effects of shear stress and elongational stress, on cells with nuclei of different sizes, representing either neutrophils (small nucleus) or lympohcytes (large nucleus), was investigated. Results: Under both elongational and shear stress the cells with the smaller nuclei deformed more than those with the larger nuclei. This could help to explain why neutrophils are damaged more than lymphocytes in VADs. Conclusions: A numerical model of leukocyte deformation has been created and used to investigate cell deformation under elongational and shear stresses." @default.
- W2781542011 created "2018-01-12" @default.
- W2781542011 creator A5005469133 @default.
- W2781542011 creator A5009967658 @default.
- W2781542011 creator A5011721772 @default.
- W2781542011 creator A5045642972 @default.
- W2781542011 creator A5050011887 @default.
- W2781542011 creator A5050698450 @default.
- W2781542011 creator A5052077932 @default.
- W2781542011 creator A5061152501 @default.
- W2781542011 creator A5075085339 @default.
- W2781542011 creator A5085120063 @default.
- W2781542011 date "2017-09-01" @default.
- W2781542011 modified "2023-09-23" @default.
- W2781542011 title "NUMERICAL MODELLING OF LEUKOCYTE DEFORMATION IN VENTRICULAR ASSIST DEVICES" @default.
- W2781542011 hasPublicationYear "2017" @default.
- W2781542011 type Work @default.
- W2781542011 sameAs 2781542011 @default.
- W2781542011 citedByCount "0" @default.
- W2781542011 crossrefType "journal-article" @default.
- W2781542011 hasAuthorship W2781542011A5005469133 @default.
- W2781542011 hasAuthorship W2781542011A5009967658 @default.
- W2781542011 hasAuthorship W2781542011A5011721772 @default.
- W2781542011 hasAuthorship W2781542011A5045642972 @default.
- W2781542011 hasAuthorship W2781542011A5050011887 @default.
- W2781542011 hasAuthorship W2781542011A5050698450 @default.
- W2781542011 hasAuthorship W2781542011A5052077932 @default.
- W2781542011 hasAuthorship W2781542011A5061152501 @default.
- W2781542011 hasAuthorship W2781542011A5075085339 @default.
- W2781542011 hasAuthorship W2781542011A5085120063 @default.
- W2781542011 hasConcept C121332964 @default.
- W2781542011 hasConcept C127413603 @default.
- W2781542011 hasConcept C138885662 @default.
- W2781542011 hasConcept C153005164 @default.
- W2781542011 hasConcept C159985019 @default.
- W2781542011 hasConcept C169760540 @default.
- W2781542011 hasConcept C192562407 @default.
- W2781542011 hasConcept C204366326 @default.
- W2781542011 hasConcept C21036866 @default.
- W2781542011 hasConcept C21141959 @default.
- W2781542011 hasConcept C2780723820 @default.
- W2781542011 hasConcept C2781345722 @default.
- W2781542011 hasConcept C41895202 @default.
- W2781542011 hasConcept C57879066 @default.
- W2781542011 hasConcept C78519656 @default.
- W2781542011 hasConcept C86803240 @default.
- W2781542011 hasConcept C96035792 @default.
- W2781542011 hasConceptScore W2781542011C121332964 @default.
- W2781542011 hasConceptScore W2781542011C127413603 @default.
- W2781542011 hasConceptScore W2781542011C138885662 @default.
- W2781542011 hasConceptScore W2781542011C153005164 @default.
- W2781542011 hasConceptScore W2781542011C159985019 @default.
- W2781542011 hasConceptScore W2781542011C169760540 @default.
- W2781542011 hasConceptScore W2781542011C192562407 @default.
- W2781542011 hasConceptScore W2781542011C204366326 @default.
- W2781542011 hasConceptScore W2781542011C21036866 @default.
- W2781542011 hasConceptScore W2781542011C21141959 @default.
- W2781542011 hasConceptScore W2781542011C2780723820 @default.
- W2781542011 hasConceptScore W2781542011C2781345722 @default.
- W2781542011 hasConceptScore W2781542011C41895202 @default.
- W2781542011 hasConceptScore W2781542011C57879066 @default.
- W2781542011 hasConceptScore W2781542011C78519656 @default.
- W2781542011 hasConceptScore W2781542011C86803240 @default.
- W2781542011 hasConceptScore W2781542011C96035792 @default.
- W2781542011 hasIssue "8" @default.
- W2781542011 hasLocation W27815420111 @default.
- W2781542011 hasOpenAccess W2781542011 @default.
- W2781542011 hasPrimaryLocation W27815420111 @default.
- W2781542011 hasRelatedWork W1481988525 @default.
- W2781542011 hasRelatedWork W177127349 @default.
- W2781542011 hasRelatedWork W1804383791 @default.
- W2781542011 hasRelatedWork W1973282289 @default.
- W2781542011 hasRelatedWork W1973635344 @default.
- W2781542011 hasRelatedWork W2003144808 @default.
- W2781542011 hasRelatedWork W2021607921 @default.
- W2781542011 hasRelatedWork W2072559633 @default.
- W2781542011 hasRelatedWork W2095118408 @default.
- W2781542011 hasRelatedWork W2127903994 @default.
- W2781542011 hasRelatedWork W2165221278 @default.
- W2781542011 hasRelatedWork W2321836867 @default.
- W2781542011 hasRelatedWork W2388239960 @default.
- W2781542011 hasRelatedWork W2400296682 @default.
- W2781542011 hasRelatedWork W2406673357 @default.
- W2781542011 hasRelatedWork W2940837780 @default.
- W2781542011 hasRelatedWork W3187490531 @default.
- W2781542011 hasRelatedWork W3206820263 @default.
- W2781542011 hasRelatedWork W587111377 @default.
- W2781542011 hasRelatedWork W6759986 @default.
- W2781542011 hasVolume "40" @default.
- W2781542011 isParatext "false" @default.
- W2781542011 isRetracted "false" @default.
- W2781542011 magId "2781542011" @default.
- W2781542011 workType "article" @default.