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- W2781585845 abstract "MiRNAs were shown to participate in development of autoimmune inflammatory process in multiple sclerosis (MS). To investigate miRNAs involvement in relapse-remission MS course, we analyzed expression of immune-related miRNAs in PBMC of treatment-naïve relapsing and remitting MS patients and healthy controls. The upregulation of miR-126-3p, miR-146b-5p, miR-155, miR-196a-5p, miR-21-5p, miR-223-3p, miR-326 and miR-379-5p in remission compared to relapse was observed; when apply gender stratification, miR-223-3p and miR-379-5p were upregulated only in men. Therefore, miRNAs play essential role in maintaining stable MS course and this process has certain gender-specific differences." @default.
- W2781585845 created "2018-01-12" @default.
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- W2781585845 date "2018-04-01" @default.
- W2781585845 modified "2023-10-14" @default.
- W2781585845 title "Immune-related miRNA expression patterns in peripheral blood mononuclear cells differ in multiple sclerosis relapse and remission" @default.
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- W2781585845 doi "https://doi.org/10.1016/j.jneuroim.2018.01.005" @default.
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