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• W2782190664 abstract "To explore the expression profiles of microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and mRNAs in oesophageal squamous cell carcinoma (ESCC) in order to construct an oesophageal cancer-specific competing endogenous RNA (ceRNA) network.In this work, the expression data of miRNAs, lncRNAs, and mRNAs in ESCC were obtained. An oesophageal cancer-specific ceRNA network was then constructed and investigated.CeRNAs have the ability to reduce the targeting activity of miRNAs, leading to the de-repression of specific mRNAs with common miRNA response elements. CeRNA interactions have a critical effect in gene regulation and cancer development.This study suggests a novel perspective on potential oesophageal cancer mechanisms as well as novel pathways for modulating ceRNA networks for treating cancers." @default.
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• W2782190664 date "2018-01-07" @default.
• W2782190664 modified "2023-10-18" @default.
• W2782190664 title "Construction of an oesophageal cancer-specific ceRNA network based on miRNA, lncRNA, and mRNA expression data" @default.
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• W2782190664 doi "https://doi.org/10.3748/wjg.v24.i1.23" @default.
• W2782190664 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5757122" @default.
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• W2782190664 hasPublicationYear "2018" @default.
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