FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2782406802> ?p ?o ?g. }

• W2782406802 endingPage "13" @default.
• W2782406802 startingPage "7" @default.
• W2782406802 abstract "Understanding the timing and pattern of cancer recurrence is essential to explain the causes of treatment failure. We investigated the recurrence pattern and rate over time in patients with completely resected N1-stage II lung adenocarcinoma.We retrospectively reviewed the medical records of 333 patients who underwent complete surgical resection for N1-stage II lung adenocarcinoma.The median recurrence-free survival (RFS) was 38.8 months and the 5-year RFS rate was 39.6%. Left-sided tumors, large tumor size, and lymph node (LN) ratio higher than 0.15 were significantly correlated with a worse RFS, whereas female sex, direct LN involvement, and adjuvant chemotherapy were significantly correlated with a better RFS. Among the 182 patients who experienced recurrences, 46 (25.3%) had only loco-regional recurrences and 136 (74.7%) had distant metastases. The organs most commonly involved in initial recurrence were the lungs (n = 89, 48.9%), followed by bone (n = 41, 22.5%) and the brain (n = 38, 20.9%). The recurrence hazard curve for the entire study population demonstrated a similarly shaped and sized initial and second peak at 15 and 23 months, and a third smaller peak during the fourth year. The recurrence hazard curve of patients who received adjuvant chemotherapy exhibited a more delayed and smaller first peak than those who did not receive adjuvant chemotherapy. The patients treated with adjuvant chemotherapy had a lower rate of distant metastasis (p = 0.037); adjuvant chemotherapy had no effect on brain metastasis (p = 0.640).In the present cohort, the hazard curves suggested that bone and brain recurrences exhibited an earlier first peak, while lung recurrences presented later. Adjuvant chemotherapy not only reduced the recurrence hazard but also delayed the recurrence and altered the pattern of recurrence. However, these results need to be confirmed in a prospective study." @default.
• W2782406802 created "2018-01-12" @default.
• W2782406802 creator A5005044285 @default.
• W2782406802 creator A5010364211 @default.
• W2782406802 creator A5016970576 @default.
• W2782406802 creator A5030107272 @default.
• W2782406802 creator A5030926405 @default.
• W2782406802 creator A5034739279 @default.
• W2782406802 creator A5045904442 @default.
• W2782406802 creator A5046938706 @default.
• W2782406802 creator A5049872669 @default.
• W2782406802 creator A5051553873 @default.
• W2782406802 creator A5052490373 @default.
• W2782406802 creator A5067659520 @default.
• W2782406802 creator A5081560950 @default.
• W2782406802 creator A5082025437 @default.
• W2782406802 date "2018-03-01" @default.
• W2782406802 modified "2023-09-27" @default.
• W2782406802 title "Temporal and regional distribution of initial recurrence site in completely resected N1-stage II lung adenocarcinoma: The effect of postoperative adjuvant chemotherapy" @default.
• W2782406802 cites W1740332796 @default.
• W2782406802 cites W1978846353 @default.
• W2782406802 cites W1991340699 @default.
• W2782406802 cites W1994361267 @default.
• W2782406802 cites W2001210023 @default.
• W2782406802 cites W2004682512 @default.
• W2782406802 cites W2027786292 @default.
• W2782406802 cites W2029554868 @default.
• W2782406802 cites W2033791152 @default.
• W2782406802 cites W2036611968 @default.
• W2782406802 cites W2040211532 @default.
• W2782406802 cites W2047213739 @default.
• W2782406802 cites W2050811691 @default.
• W2782406802 cites W2061137205 @default.
• W2782406802 cites W2061302727 @default.
• W2782406802 cites W2070068444 @default.
• W2782406802 cites W2080497228 @default.
• W2782406802 cites W2081841979 @default.
• W2782406802 cites W2094654587 @default.
• W2782406802 cites W2100379216 @default.
• W2782406802 cites W2104877698 @default.
• W2782406802 cites W2111725799 @default.
• W2782406802 cites W2113676600 @default.
• W2782406802 cites W2120587170 @default.
• W2782406802 cites W2141094011 @default.
• W2782406802 cites W2146818043 @default.
• W2782406802 cites W2161942450 @default.
• W2782406802 cites W2235547202 @default.
• W2782406802 cites W2312188622 @default.
• W2782406802 doi "https://doi.org/10.1016/j.lungcan.2018.01.004" @default.
• W2782406802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29496256" @default.
• W2782406802 hasPublicationYear "2018" @default.
• W2782406802 type Work @default.
• W2782406802 sameAs 2782406802 @default.
• W2782406802 citedByCount "11" @default.
• W2782406802 countsByYear W27824068022018 @default.
• W2782406802 countsByYear W27824068022019 @default.
• W2782406802 countsByYear W27824068022020 @default.
• W2782406802 countsByYear W27824068022021 @default.
• W2782406802 countsByYear W27824068022023 @default.
• W2782406802 crossrefType "journal-article" @default.
• W2782406802 hasAuthorship W2782406802A5005044285 @default.
• W2782406802 hasAuthorship W2782406802A5010364211 @default.
• W2782406802 hasAuthorship W2782406802A5016970576 @default.
• W2782406802 hasAuthorship W2782406802A5030107272 @default.
• W2782406802 hasAuthorship W2782406802A5030926405 @default.
• W2782406802 hasAuthorship W2782406802A5034739279 @default.
• W2782406802 hasAuthorship W2782406802A5045904442 @default.
• W2782406802 hasAuthorship W2782406802A5046938706 @default.
• W2782406802 hasAuthorship W2782406802A5049872669 @default.
• W2782406802 hasAuthorship W2782406802A5051553873 @default.
• W2782406802 hasAuthorship W2782406802A5052490373 @default.
• W2782406802 hasAuthorship W2782406802A5067659520 @default.
• W2782406802 hasAuthorship W2782406802A5081560950 @default.
• W2782406802 hasAuthorship W2782406802A5082025437 @default.
• W2782406802 hasConcept C121608353 @default.
• W2782406802 hasConcept C126322002 @default.
• W2782406802 hasConcept C141071460 @default.
• W2782406802 hasConcept C143998085 @default.
• W2782406802 hasConcept C146357865 @default.
• W2782406802 hasConcept C151730666 @default.
• W2782406802 hasConcept C207103383 @default.
• W2782406802 hasConcept C2776694085 @default.
• W2782406802 hasConcept C2777714996 @default.
• W2782406802 hasConcept C2777863537 @default.
• W2782406802 hasConcept C2777982462 @default.
• W2782406802 hasConcept C2779013556 @default.
• W2782406802 hasConcept C2780849966 @default.
• W2782406802 hasConcept C2781182431 @default.
• W2782406802 hasConcept C2908647359 @default.
• W2782406802 hasConcept C3018227240 @default.
• W2782406802 hasConcept C44249647 @default.
• W2782406802 hasConcept C50382708 @default.
• W2782406802 hasConcept C530470458 @default.
• W2782406802 hasConcept C71924100 @default.
• W2782406802 hasConcept C72563966 @default.
• W2782406802 hasConcept C86803240 @default.
• W2782406802 hasConcept C90924648 @default.
• W2782406802 hasConcept C99454951 @default.

• next