FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2782478567> ?p ?o ?g. }

• W2782478567 abstract "// Huihui Cheng 1 , Saisai Li 1 , Lulu Zhou 1 , Hui Luo 1 , Zhaojun Shen 1 and Xueqiong Zhu 1 1 Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China Correspondence to: Xueqiong Zhu, email: zjwzzxq@163.com Keywords : nestin; solid tumors; prognosis; meta-analysis Received: July 19, 2017     Accepted: November 14, 2017     Epub: January 03, 2018 Abstract Background: Nestin, as a marker of cancer stem cells, has recently been reported frequently in the pathogenesis and development of human solid tumors. However, the prognostic role of Nestin in patients with solid tumors remains inconclusive. Here, we performed this meta-analysis of relevant studies published on the topic to quantitatively evaluate the prognostic significance of Nestin in solid tumors. Methods: We performed systematically electronic and manual searches through the databases of Pubmed and Embase for titles and abstracts. The pooled hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) of overall survival (OS) or cancer-specific survival (CSS) or disease-free survival (DFS)/progression-free survival (PFS)/recurrent-free survival (RFS)/ event-free survival (EFS) were calculated to evaluate the prognostic value of Nestin expression in patients with solid tumors. Results: A total of 43 studies involving 6,068 participants were included in the study. Nestin over-expression was associated with statistically significant poor OS (pooled HR = 1.74, 95% CI = 1.48-2.05, P <0.001) and shorter CSS (pooled HR = 2.35, 95% CI = 1.87-2.97, P <0.001) and shorter DFS/ PFS/ RFS/EFS (pooled HR = 1.77, 95% CI = 1.41-2.23, P <0.001) in solid tumors. Further subgroup analyses showed that different analysis model (univariate or multivariate model), sample-size (≤ 105 or >105), ethnicity (Asia or Europe or South America), primary tumor location, and method for data collection (direct extraction or indirect extraction) didn’t alter the negative prognostic effect of Nestin over-expression on OS. For DFS/ PFS/ RFS/ EFS, subgroup analyses based on statistical analysis model, sample size and study ethnicity also showed the negative prognostic role of Nestin. Conclusion: Nestin over-expression was associated with shorter survival in human solid tumors. Nestin could be a valuable prognosis biomarker of some solid tumors." @default.
• W2782478567 created "2018-01-12" @default.
• W2782478567 creator A5012906398 @default.
• W2782478567 creator A5023127724 @default.
• W2782478567 creator A5036286066 @default.
• W2782478567 creator A5046113578 @default.
• W2782478567 creator A5047736510 @default.
• W2782478567 creator A5057356935 @default.
• W2782478567 date "2018-01-04" @default.
• W2782478567 modified "2023-10-04" @default.
• W2782478567 title "WITHDRAWN: Nestin over-expression predicts poor prognosis in patients with solid tumors: a meta- analysis" @default.
• W2782478567 doi "https://doi.org/10.18632/oncotarget.23876" @default.
• W2782478567 hasPublicationYear "2018" @default.
• W2782478567 type Work @default.
• W2782478567 sameAs 2782478567 @default.
• W2782478567 citedByCount "0" @default.
• W2782478567 crossrefType "journal-article" @default.
• W2782478567 hasAuthorship W2782478567A5012906398 @default.
• W2782478567 hasAuthorship W2782478567A5023127724 @default.
• W2782478567 hasAuthorship W2782478567A5036286066 @default.
• W2782478567 hasAuthorship W2782478567A5046113578 @default.
• W2782478567 hasAuthorship W2782478567A5047736510 @default.
• W2782478567 hasAuthorship W2782478567A5057356935 @default.
• W2782478567 hasBestOaLocation W27824785671 @default.
• W2782478567 hasConcept C121608353 @default.
• W2782478567 hasConcept C126322002 @default.
• W2782478567 hasConcept C136834591 @default.
• W2782478567 hasConcept C143998085 @default.
• W2782478567 hasConcept C207103383 @default.
• W2782478567 hasConcept C2777738006 @default.
• W2782478567 hasConcept C2780739268 @default.
• W2782478567 hasConcept C28328180 @default.
• W2782478567 hasConcept C2993640289 @default.
• W2782478567 hasConcept C3019894029 @default.
• W2782478567 hasConcept C44249647 @default.
• W2782478567 hasConcept C54355233 @default.
• W2782478567 hasConcept C71924100 @default.
• W2782478567 hasConcept C86803240 @default.
• W2782478567 hasConcept C95190672 @default.
• W2782478567 hasConceptScore W2782478567C121608353 @default.
• W2782478567 hasConceptScore W2782478567C126322002 @default.
• W2782478567 hasConceptScore W2782478567C136834591 @default.
• W2782478567 hasConceptScore W2782478567C143998085 @default.
• W2782478567 hasConceptScore W2782478567C207103383 @default.
• W2782478567 hasConceptScore W2782478567C2777738006 @default.
• W2782478567 hasConceptScore W2782478567C2780739268 @default.
• W2782478567 hasConceptScore W2782478567C28328180 @default.
• W2782478567 hasConceptScore W2782478567C2993640289 @default.
• W2782478567 hasConceptScore W2782478567C3019894029 @default.
• W2782478567 hasConceptScore W2782478567C44249647 @default.
• W2782478567 hasConceptScore W2782478567C54355233 @default.
• W2782478567 hasConceptScore W2782478567C71924100 @default.
• W2782478567 hasConceptScore W2782478567C86803240 @default.
• W2782478567 hasConceptScore W2782478567C95190672 @default.
• W2782478567 hasIssue "5" @default.
• W2782478567 hasLocation W27824785671 @default.
• W2782478567 hasOpenAccess W2782478567 @default.
• W2782478567 hasPrimaryLocation W27824785671 @default.
• W2782478567 hasRelatedWork W166409149 @default.
• W2782478567 hasRelatedWork W1900595920 @default.
• W2782478567 hasRelatedWork W2130616545 @default.
• W2782478567 hasRelatedWork W2748373020 @default.
• W2782478567 hasRelatedWork W2810008553 @default.
• W2782478567 hasRelatedWork W2889691785 @default.
• W2782478567 hasRelatedWork W3157589766 @default.
• W2782478567 hasRelatedWork W3185003217 @default.
• W2782478567 hasRelatedWork W4206071870 @default.
• W2782478567 hasRelatedWork W4309666155 @default.
• W2782478567 hasVolume "0" @default.
• W2782478567 isParatext "false" @default.
• W2782478567 isRetracted "false" @default.
• W2782478567 magId "2782478567" @default.
• W2782478567 workType "article" @default.