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- W2782561013 startingPage "18" @default.
- W2782561013 abstract "Aging is the most important risk factor for major human lifestyle diseases, including cancer, neurological and cardiometabolic disorders. Due to the complex interplay between genetics, lifestyle and environmental factors, some individuals seem to age faster than others, whereas centenarians seem to have a slower aging process. Therefore, a biochemical biomarker reflecting the relative biological age would be helpful to predict an individual's health status and aging disease risk. Although it is already known for years that cumulative epigenetic changes occur upon aging, DNA methylation patterns were only recently used to construct an epigenetic clock predictor for biological age, which is a measure of how well your body functions compared to your chronological age. Moreover, the epigenetic DNA methylation clock signature is increasingly applied as a biomarker to estimate aging disease susceptibility and mortality risk. Finally, the epigenetic clock signature could be used as a lifestyle management tool to monitor healthy aging, to evaluate preventive interventions against chronic aging disorders and to extend healthy lifespan. Dissecting the mechanism of the epigenetic aging clock will yield valuable insights into the aging process and how it can be manipulated to improve health span." @default.
- W2782561013 created "2018-01-26" @default.
- W2782561013 creator A5035131047 @default.
- W2782561013 creator A5052226197 @default.
- W2782561013 date "2018-09-01" @default.
- W2782561013 modified "2023-10-12" @default.
- W2782561013 title "Back to the future: Epigenetic clock plasticity towards healthy aging" @default.
- W2782561013 cites W1135614030 @default.
- W2782561013 cites W1530934778 @default.
- W2782561013 cites W1606128340 @default.
- W2782561013 cites W1639076783 @default.
- W2782561013 cites W164032219 @default.
- W2782561013 cites W1692222554 @default.
- W2782561013 cites W1816060061 @default.
- W2782561013 cites W1853227327 @default.
- W2782561013 cites W1893305947 @default.
- W2782561013 cites W1966336914 @default.
- W2782561013 cites W1966985930 @default.
- W2782561013 cites W1974047233 @default.
- W2782561013 cites W1974372333 @default.
- W2782561013 cites W1983899753 @default.
- W2782561013 cites W1984589574 @default.
- W2782561013 cites W1985444222 @default.
- W2782561013 cites W1986462247 @default.
- W2782561013 cites W1990958459 @default.
- W2782561013 cites W1999377691 @default.
- W2782561013 cites W2014110447 @default.
- W2782561013 cites W2014945558 @default.
- W2782561013 cites W2015364707 @default.
- W2782561013 cites W2022152889 @default.
- W2782561013 cites W2022526122 @default.
- W2782561013 cites W2023639434 @default.
- W2782561013 cites W2036284273 @default.
- W2782561013 cites W2038779500 @default.
- W2782561013 cites W2039669402 @default.
- W2782561013 cites W2042913529 @default.
- W2782561013 cites W2045742891 @default.
- W2782561013 cites W2050377050 @default.
- W2782561013 cites W2054863651 @default.
- W2782561013 cites W2055237453 @default.
- W2782561013 cites W2056760636 @default.
- W2782561013 cites W2057986314 @default.
- W2782561013 cites W2061809258 @default.
- W2782561013 cites W2062149404 @default.
- W2782561013 cites W2063613391 @default.
- W2782561013 cites W2065973763 @default.
- W2782561013 cites W2072130124 @default.
- W2782561013 cites W2077359776 @default.
- W2782561013 cites W2086088557 @default.
- W2782561013 cites W2091262245 @default.
- W2782561013 cites W2094156327 @default.
- W2782561013 cites W2097743364 @default.
- W2782561013 cites W2098251879 @default.
- W2782561013 cites W2099343472 @default.
- W2782561013 cites W2102093038 @default.
- W2782561013 cites W2102893853 @default.
- W2782561013 cites W2105767248 @default.
- W2782561013 cites W2108664872 @default.
- W2782561013 cites W2110470531 @default.
- W2782561013 cites W2111775559 @default.
- W2782561013 cites W2113296450 @default.
- W2782561013 cites W2113649341 @default.
- W2782561013 cites W2114390263 @default.
- W2782561013 cites W2121091193 @default.
- W2782561013 cites W2123032740 @default.
- W2782561013 cites W2124167740 @default.
- W2782561013 cites W2124407126 @default.
- W2782561013 cites W2124913456 @default.
- W2782561013 cites W2125334940 @default.
- W2782561013 cites W2125734753 @default.
- W2782561013 cites W2126525177 @default.
- W2782561013 cites W2127196115 @default.
- W2782561013 cites W2129155846 @default.
- W2782561013 cites W2130189740 @default.
- W2782561013 cites W2130318234 @default.
- W2782561013 cites W2131442620 @default.
- W2782561013 cites W2133469113 @default.
- W2782561013 cites W2134555277 @default.
- W2782561013 cites W2136157968 @default.
- W2782561013 cites W2136691282 @default.
- W2782561013 cites W2142053177 @default.
- W2782561013 cites W2142181725 @default.
- W2782561013 cites W2143086385 @default.
- W2782561013 cites W2144535782 @default.
- W2782561013 cites W2144787350 @default.
- W2782561013 cites W2146794662 @default.
- W2782561013 cites W2147707618 @default.
- W2782561013 cites W2150310487 @default.
- W2782561013 cites W2150708667 @default.
- W2782561013 cites W2153127464 @default.
- W2782561013 cites W2154421168 @default.
- W2782561013 cites W2156413526 @default.
- W2782561013 cites W2158033629 @default.
- W2782561013 cites W2158554646 @default.
- W2782561013 cites W2159536887 @default.
- W2782561013 cites W2160704282 @default.
- W2782561013 cites W2161575387 @default.
- W2782561013 cites W2163887613 @default.