FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2782686543> ?p ?o ?g. }

• W2782686543 endingPage "115" @default.
• W2782686543 startingPage "110" @default.
• W2782686543 abstract "The prognostic relevance of epilepsy at glioblastoma (GBMs) onset is still under debate. In this study, we analyzed the value of epilepsy and other prognostic factors on GBMs survival. We retrospectively analyzed the clinical, radiological, surgical and histological data in 139 GBMs. Seizures were the presenting symptoms in 50 patients out of 139 (35.9%). 123 patients (88%) were treated with craniotomy and tumor resection while 16 (12%) with biopsy. The median overall survival was 9.9 months from surgery. At univariable Cox regression, the factors that significantly improved survival were age less than 65 years (P = 0.0015), focal without impairment of consciousness seizures at presentation (P = 0.043), complete surgical resection (P < 0.001), pre-operative Karnofsky performance status (KPS) > 70 (P = 0.015), frontal location (P < 0.001), radiotherapy (XRT) plus concomitant and adjuvant TMZ (P < 0.001). A multivariable Cox regression showed that the complete surgical resection (P < 0.0001), age less than 65 years (P = 0.008), frontal location (P = 0.0001) and XRT adjuvant temozolomide (TMZ) (P < 0.0001) were independent factors on longer survival. In our series epilepsy at presentation is not an independent prognostic factor for longer survival in GBM patients. Only in the subgroup of patients with focal seizures without impairment of consciousness, epilepsy was associated with an increased significant overall survival at univariate analysis (P = 0.043). Main independent factors for relatively favorable GBMs outcome are complete tumor resection plus combined XRT-TMZ, frontal location and patient age below 65 years old." @default.
• W2782686543 created "2018-01-26" @default.
• W2782686543 creator A5021761534 @default.
• W2782686543 creator A5025475717 @default.
• W2782686543 creator A5061244641 @default.
• W2782686543 creator A5066383337 @default.
• W2782686543 creator A5079989367 @default.
• W2782686543 creator A5081573235 @default.
• W2782686543 date "2018-01-01" @default.
• W2782686543 modified "2023-10-02" @default.
• W2782686543 title "Prognostic Factors in Glioblastoma: Is There a Role for Epilepsy?" @default.
• W2782686543 cites W1512760401 @default.
• W2782686543 cites W2008854570 @default.
• W2782686543 cites W2052669444 @default.
• W2782686543 cites W2069153453 @default.
• W2782686543 cites W2096287682 @default.
• W2782686543 cites W2098180609 @default.
• W2782686543 cites W2247462887 @default.
• W2782686543 cites W2345459375 @default.
• W2782686543 cites W2475320130 @default.
• W2782686543 cites W2510395655 @default.
• W2782686543 cites W2562695356 @default.
• W2782686543 cites W2610403529 @default.
• W2782686543 cites W2619662012 @default.
• W2782686543 cites W999015623 @default.
• W2782686543 doi "https://doi.org/10.2176/nmc.oa.2017-0167" @default.
• W2782686543 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5929919" @default.
• W2782686543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29343677" @default.
• W2782686543 hasPublicationYear "2018" @default.
• W2782686543 type Work @default.
• W2782686543 sameAs 2782686543 @default.
• W2782686543 citedByCount "18" @default.
• W2782686543 countsByYear W27826865432018 @default.
• W2782686543 countsByYear W27826865432019 @default.
• W2782686543 countsByYear W27826865432020 @default.
• W2782686543 countsByYear W27826865432021 @default.
• W2782686543 countsByYear W27826865432022 @default.
• W2782686543 countsByYear W27826865432023 @default.
• W2782686543 crossrefType "journal-article" @default.
• W2782686543 hasAuthorship W2782686543A5021761534 @default.
• W2782686543 hasAuthorship W2782686543A5025475717 @default.
• W2782686543 hasAuthorship W2782686543A5061244641 @default.
• W2782686543 hasAuthorship W2782686543A5066383337 @default.
• W2782686543 hasAuthorship W2782686543A5079989367 @default.
• W2782686543 hasAuthorship W2782686543A5081573235 @default.
• W2782686543 hasBestOaLocation W27826865431 @default.
• W2782686543 hasConcept C118552586 @default.
• W2782686543 hasConcept C121608353 @default.
• W2782686543 hasConcept C126322002 @default.
• W2782686543 hasConcept C141071460 @default.
• W2782686543 hasConcept C143998085 @default.
• W2782686543 hasConcept C144301174 @default.
• W2782686543 hasConcept C2776194525 @default.
• W2782686543 hasConcept C2777389519 @default.
• W2782686543 hasConcept C2777982462 @default.
• W2782686543 hasConcept C2778186239 @default.
• W2782686543 hasConcept C2778227246 @default.
• W2782686543 hasConcept C2778871575 @default.
• W2782686543 hasConcept C2779384505 @default.
• W2782686543 hasConcept C2780803581 @default.
• W2782686543 hasConcept C38180746 @default.
• W2782686543 hasConcept C502942594 @default.
• W2782686543 hasConcept C50382708 @default.
• W2782686543 hasConcept C509974204 @default.
• W2782686543 hasConcept C71924100 @default.
• W2782686543 hasConceptScore W2782686543C118552586 @default.
• W2782686543 hasConceptScore W2782686543C121608353 @default.
• W2782686543 hasConceptScore W2782686543C126322002 @default.
• W2782686543 hasConceptScore W2782686543C141071460 @default.
• W2782686543 hasConceptScore W2782686543C143998085 @default.
• W2782686543 hasConceptScore W2782686543C144301174 @default.
• W2782686543 hasConceptScore W2782686543C2776194525 @default.
• W2782686543 hasConceptScore W2782686543C2777389519 @default.
• W2782686543 hasConceptScore W2782686543C2777982462 @default.
• W2782686543 hasConceptScore W2782686543C2778186239 @default.
• W2782686543 hasConceptScore W2782686543C2778227246 @default.
• W2782686543 hasConceptScore W2782686543C2778871575 @default.
• W2782686543 hasConceptScore W2782686543C2779384505 @default.
• W2782686543 hasConceptScore W2782686543C2780803581 @default.
• W2782686543 hasConceptScore W2782686543C38180746 @default.
• W2782686543 hasConceptScore W2782686543C502942594 @default.
• W2782686543 hasConceptScore W2782686543C50382708 @default.
• W2782686543 hasConceptScore W2782686543C509974204 @default.
• W2782686543 hasConceptScore W2782686543C71924100 @default.
• W2782686543 hasIssue "3" @default.
• W2782686543 hasLocation W27826865431 @default.
• W2782686543 hasLocation W27826865432 @default.
• W2782686543 hasLocation W27826865433 @default.
• W2782686543 hasLocation W27826865434 @default.
• W2782686543 hasLocation W27826865435 @default.
• W2782686543 hasOpenAccess W2782686543 @default.
• W2782686543 hasPrimaryLocation W27826865431 @default.
• W2782686543 hasRelatedWork W1944863716 @default.
• W2782686543 hasRelatedWork W2030471898 @default.
• W2782686543 hasRelatedWork W2042969729 @default.
• W2782686543 hasRelatedWork W2329162537 @default.
• W2782686543 hasRelatedWork W2414949291 @default.
• W2782686543 hasRelatedWork W2417049953 @default.

• next