Matches in SemOpenAlex for { <https://semopenalex.org/work/W2782981736> ?p ?o ?g. }
- W2782981736 abstract "Breast milk is the first choice in feeding newborn infants and provides multiple benefits for their growth and development. Staphylococcus aureus usually exists in breast milk and is considered one of the most important causative infective agents. To be effective in preventing and controlling S. aureus infections among infants, the aim of this study was to determine the occurrence and molecular characteristics of S. aureus isolated from 1102 samples of breast milk between 2015 and 2016 in Shanghai, China. Out of 71 S. aureus strains isolated, 15(21.1%,15/71) were MRSA and all the strains were characterized by spa typing, Multi-Locus Sequence Typing, SCCmec typing, antibiotic resistance testing and virulence-associated genes. A total of 18 distinct sequence types (STs) and 36 spa types were identified within the 71 isolates, among which the most frequently represented was ST398 (19.7%, 14/71), followed by ST7 (18.3%, 13/71), ST59 (16.9%, 12/71). The three predominant STs accounted for more than one half of all S. aureus isolates. The most prevalent spa types were t091(12.7%,9/71), followed by t571(8.5%,6/71), t189(7.0%,5/71), t034(5.6%,4/71), t437(5.6%,4/71) and t701(4.2%,3/71). All MRSA isolates belonged to SCCmec IV and V, accounting for 66.7% and 33.3% respectively. Notably, 23 (32.4%) S. aureus strains were multidrug resistance (MDR), including 4 (5.6%) MRSA and 19 (26.8%) MSSA strains, and MDR isolates were mostly resistant to penicillin, erythromycin and clindamycin. All isolates exhibited simultaneous carriage of at least 5 of 33 possible virulence genes and the most prevalent genes detected were icaA(100%), clfA(100%), hla (100%), sdrC(94.4%), hlg2(88.7%), lukE(57.8%). 39(54.9%, 39/71) isolates, including 9 (12.7%) of MRSA isolates, harbored ≥10 tested virulence genes evaluated in this study. The pvl gene was detected in 8 strains, which represented 5 different STs, with ST59 being the most one. Overall, our findings showed that S aureus strains isolated from breast milk were mainly MSSA (78.9%, 56/71) and exhibited high genetic diversity in Shanghai area of China. Breast milk was a reservoir for LA-SA (ST398) and CA-SA (ST59),which was likely a vehicle for transmission of multidrug-resistant S.aureus and MRSA lineages. This is a potential public health risk and highlights the need for good hygiene" @default.
- W2782981736 created "2018-01-26" @default.
- W2782981736 creator A5018931479 @default.
- W2782981736 creator A5027176507 @default.
- W2782981736 creator A5045840604 @default.
- W2782981736 creator A5052586605 @default.
- W2782981736 creator A5068258954 @default.
- W2782981736 date "2018-01-11" @default.
- W2782981736 modified "2023-10-01" @default.
- W2782981736 title "Breast Milk Is a Potential Reservoir for Livestock-Associated Staphylococcus aureus and Community-Associated Staphylococcus aureus in Shanghai, China" @default.
- W2782981736 cites W1748063039 @default.
- W2782981736 cites W1902372910 @default.
- W2782981736 cites W1963708109 @default.
- W2782981736 cites W1973944724 @default.
- W2782981736 cites W1976843427 @default.
- W2782981736 cites W1984577847 @default.
- W2782981736 cites W2002551385 @default.
- W2782981736 cites W2018774199 @default.
- W2782981736 cites W2026255431 @default.
- W2782981736 cites W2034166141 @default.
- W2782981736 cites W2034631514 @default.
- W2782981736 cites W2035445858 @default.
- W2782981736 cites W2040559263 @default.
- W2782981736 cites W2043082319 @default.
- W2782981736 cites W2057471712 @default.
- W2782981736 cites W2064641442 @default.
- W2782981736 cites W2066890187 @default.
- W2782981736 cites W2104411795 @default.
- W2782981736 cites W2112652622 @default.
- W2782981736 cites W2125211897 @default.
- W2782981736 cites W2125898425 @default.
- W2782981736 cites W2129202443 @default.
- W2782981736 cites W2146802311 @default.
- W2782981736 cites W2154050435 @default.
- W2782981736 cites W2157079807 @default.
- W2782981736 cites W2163609676 @default.
- W2782981736 cites W2166181841 @default.
- W2782981736 cites W2170024040 @default.
- W2782981736 cites W2190538146 @default.
- W2782981736 cites W226760519 @default.
- W2782981736 cites W2314649741 @default.
- W2782981736 cites W2432506472 @default.
- W2782981736 cites W2569299337 @default.
- W2782981736 cites W2595666784 @default.
- W2782981736 cites W2605635155 @default.
- W2782981736 cites W4247772949 @default.
- W2782981736 doi "https://doi.org/10.3389/fmicb.2017.02639" @default.
- W2782981736 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5768657" @default.
- W2782981736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29375508" @default.
- W2782981736 hasPublicationYear "2018" @default.
- W2782981736 type Work @default.
- W2782981736 sameAs 2782981736 @default.
- W2782981736 citedByCount "11" @default.
- W2782981736 countsByYear W27829817362018 @default.
- W2782981736 countsByYear W27829817362019 @default.
- W2782981736 countsByYear W27829817362020 @default.
- W2782981736 countsByYear W27829817362022 @default.
- W2782981736 countsByYear W27829817362023 @default.
- W2782981736 crossrefType "journal-article" @default.
- W2782981736 hasAuthorship W2782981736A5018931479 @default.
- W2782981736 hasAuthorship W2782981736A5027176507 @default.
- W2782981736 hasAuthorship W2782981736A5045840604 @default.
- W2782981736 hasAuthorship W2782981736A5052586605 @default.
- W2782981736 hasAuthorship W2782981736A5068258954 @default.
- W2782981736 hasBestOaLocation W27829817361 @default.
- W2782981736 hasConcept C104317684 @default.
- W2782981736 hasConcept C11701158 @default.
- W2782981736 hasConcept C133936738 @default.
- W2782981736 hasConcept C2775871700 @default.
- W2782981736 hasConcept C2776344049 @default.
- W2782981736 hasConcept C2777052132 @default.
- W2782981736 hasConcept C2777334864 @default.
- W2782981736 hasConcept C2779489039 @default.
- W2782981736 hasConcept C2781209916 @default.
- W2782981736 hasConcept C501593827 @default.
- W2782981736 hasConcept C523546767 @default.
- W2782981736 hasConcept C54355233 @default.
- W2782981736 hasConcept C55493867 @default.
- W2782981736 hasConcept C60987743 @default.
- W2782981736 hasConcept C71924100 @default.
- W2782981736 hasConcept C86803240 @default.
- W2782981736 hasConcept C89423630 @default.
- W2782981736 hasConcept C94665300 @default.
- W2782981736 hasConceptScore W2782981736C104317684 @default.
- W2782981736 hasConceptScore W2782981736C11701158 @default.
- W2782981736 hasConceptScore W2782981736C133936738 @default.
- W2782981736 hasConceptScore W2782981736C2775871700 @default.
- W2782981736 hasConceptScore W2782981736C2776344049 @default.
- W2782981736 hasConceptScore W2782981736C2777052132 @default.
- W2782981736 hasConceptScore W2782981736C2777334864 @default.
- W2782981736 hasConceptScore W2782981736C2779489039 @default.
- W2782981736 hasConceptScore W2782981736C2781209916 @default.
- W2782981736 hasConceptScore W2782981736C501593827 @default.
- W2782981736 hasConceptScore W2782981736C523546767 @default.
- W2782981736 hasConceptScore W2782981736C54355233 @default.
- W2782981736 hasConceptScore W2782981736C55493867 @default.
- W2782981736 hasConceptScore W2782981736C60987743 @default.
- W2782981736 hasConceptScore W2782981736C71924100 @default.
- W2782981736 hasConceptScore W2782981736C86803240 @default.
- W2782981736 hasConceptScore W2782981736C89423630 @default.