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• W2783019371 startingPage "424" @default.
• W2783019371 abstract "To summarise the current literature and define patterns of disease in migrant and racial groups.A structured key word search in Ovid Medline and EMBASE was undertaken in accordance with PRISMA guidelines. Studies on incidence, prevalence and disease phenotype of migrants and races compared with indigenous groups were eligible for inclusion.Thirty-three studies met the inclusion criteria. Individual studies showed significant differences in incidence, prevalence and disease phenotype between migrants or race and indigenous groups. Pooled analysis could only be undertaken for incidence studies on South Asians where there was significant heterogeneity between the studies [95% for ulcerative colitis (UC), 83% for Crohn's disease (CD)]. The difference between incidence rates was not significant with a rate ratio South Asian: Caucasian of 0.78 (95%CI: 0.22-2.78) for CD and 1.39 (95%CI: 0.84-2.32) for UC. South Asians showed consistently higher incidence and more extensive UC than the indigenous population in five countries. A similar pattern was observed for Hispanics in the United States. Bangladeshis and African Americans showed an increased risk of CD with perianal disease.This review suggests that migration and race influence the risk of developing inflammatory bowel disease. This may be due to different inherent responses upon exposure to an environmental trigger in the adopted country. Further prospective studies on homogenous migrant populations are needed to validate these observations, with a parallel arm for in-depth investigation of putative drivers." @default.
• W2783019371 created "2018-01-26" @default.
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• W2783019371 date "2018-01-21" @default.
• W2783019371 modified "2023-10-18" @default.
• W2783019371 title "Epidemiology of inflammatory bowel disease in racial and ethnic migrant groups" @default.
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• W2783019371 doi "https://doi.org/10.3748/wjg.v24.i3.424" @default.
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