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• W2783019526 endingPage "260" @default.
• W2783019526 startingPage "249" @default.
• W2783019526 abstract "Renal cell carcinoma (RCC) is the most commonly occurring solid cancer of the adult kidney with the majority of RCC cases being detected accidentally. The most aggressive subtype is clear cell RCC (ccRCC). miRNAs, a family of small noncoding RNAs regulating gene expression have been identified as key biological modulators. The von Hippel–Lindau pathway is one of the signaling pathways involved in the pathophysiology of ccRCC. Another oncogenic mechanism involves the activation of PI3K/AKT/mTOR signaling and serves as a central regulator of cell metabolism, proliferation and survival. Several studies have described the involvement of miRNA dysregulation in the pathogenesis and progression of ccRCC. These molecules can be considered as potential diagnostic and prognostic biomarkers, allowing response to therapy to be monitored." @default.
• W2783019526 created "2018-01-26" @default.
• W2783019526 creator A5001085477 @default.
• W2783019526 creator A5002735203 @default.
• W2783019526 creator A5017330209 @default.
• W2783019526 creator A5048783060 @default.
• W2783019526 date "2018-02-01" @default.
• W2783019526 modified "2023-09-25" @default.
• W2783019526 title "miRNAs as potential regulators of mTOR pathway in renal cell carcinoma" @default.
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