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- W2783104995 abstract "Peritubular myoid cells are cells located along the basal surface (outside wall) of the seminiferous tubules. They are responsible for the seminiferous tubules holding their shape and have contractile ability which promotes the transport of immotile sperm. There are notable differences between humans and rodents, with the number of layers of peritubular cells varying and the size of the extracellular matrix differing. Even after sexual maturity peritubular myoid cells continue the process of dividing. For this reason growth regulation is needed even after reaching adulthood. Peritubular cell–Sertoli cell interactions are vital to the testis and are responsible for many of the components produced in the testis. TGF-β (transforming growth factor-beta) is an agent that helps drive the maintenance of spermatogenesis. Peritubular myoid cells have been found to regulate Sertoli cell function. Leydig cell and peritubular myoid cell interactions are required for Sertoli cell development and function, indicating that peritubular myoid cells are vital to testis biology and function." @default.
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- W2783104995 date "2018-01-01" @default.
- W2783104995 modified "2023-10-17" @default.
- W2783104995 title "Peritubular Myoid Cells in Testis" @default.
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- W2783104995 doi "https://doi.org/10.1016/b978-0-12-801238-3.64361-1" @default.
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