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- W2783116403 abstract "Filamentous fungi respiratory infections, namely because of Aspergillus, Mucorales, Fusarium, or Scedosporium, show rising incidence and occur more in populations which are not classically immunosuppressed. This and their persistent dismal prognosis are the focus of this review.Both an early diagnosis, rooted on a high level of suspicion and based on clinical picture, radiology, cultural microbiological exams, fungal biomarkers, PCR and biopsy, and an early therapy, including immunorecovery, whenever possible, good antifungal selection, and surgery for source control, are paramount to maximize the outcome in these diseases. An evolving antifungal armamentarium and a more Pharmacokinetics/Pharmacodynamics-based antifungal prescription may help to improve the prognosis.Improved awareness of these infections may increase the level of suspicion, promoting early diagnosis and treatment, ideally supported with expert stewardship." @default.
- W2783116403 created "2018-01-26" @default.
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- W2783116403 date "2018-04-01" @default.
- W2783116403 modified "2023-10-14" @default.
- W2783116403 title "Aspergillus and other respiratory fungal infections in the ICU" @default.
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- W2783116403 doi "https://doi.org/10.1097/qco.0000000000000436" @default.
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