Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783126905> ?p ?o ?g. }
- W2783126905 endingPage "45" @default.
- W2783126905 startingPage "38" @default.
- W2783126905 abstract "Clade 2.3.4.4 H5N8 highly pathogenic avian influenza viruses (HPAIVs) have spread worldwide. Phylogenetic analysis identified two genetic groups of the H5N8 HPAIVs in South Korea; group A evolved further into four subgroups. Here, we examined the zoonotic potential, both in vivo and in vitro, of genetically distinct subgroups of H5N8 HPAIVs isolated in South Korea. When compared with other subgroups, A/mallard/Korea/H2102/2015 (H2102) virus caused relatively severe disease in mice at high doses. In ferrets, all H5N8 viruses replicated restrictively in the respiratory tract and did not induce significant clinical signs of influenza infection. In vitro studies, all viruses displayed a hemagglutinin phenotype that was poorly adapted for infection of mammals, although the H2102 virus exhibited higher replication kinetics at 33 °C than the others. Although H5N8 HPAIVs have not yet acquired all the characteristics required for adaptation to mammals, their ability to evolve continuously underscores the need for timely risk assessment." @default.
- W2783126905 created "2018-01-26" @default.
- W2783126905 creator A5000348178 @default.
- W2783126905 creator A5037862053 @default.
- W2783126905 creator A5041885929 @default.
- W2783126905 creator A5054463973 @default.
- W2783126905 creator A5071285237 @default.
- W2783126905 creator A5079898992 @default.
- W2783126905 creator A5086905248 @default.
- W2783126905 date "2018-03-01" @default.
- W2783126905 modified "2023-10-18" @default.
- W2783126905 title "Evaluation of the zoonotic potential of multiple subgroups of clade 2.3.4.4 influenza A (H5N8) virus" @default.
- W2783126905 cites W134344862 @default.
- W2783126905 cites W1493636931 @default.
- W2783126905 cites W1764760347 @default.
- W2783126905 cites W1953988520 @default.
- W2783126905 cites W1971455325 @default.
- W2783126905 cites W1976694080 @default.
- W2783126905 cites W1976852215 @default.
- W2783126905 cites W1986540197 @default.
- W2783126905 cites W1992510841 @default.
- W2783126905 cites W2001752145 @default.
- W2783126905 cites W2022180444 @default.
- W2783126905 cites W2023459687 @default.
- W2783126905 cites W2024970913 @default.
- W2783126905 cites W2031908280 @default.
- W2783126905 cites W2034721608 @default.
- W2783126905 cites W2039049757 @default.
- W2783126905 cites W2046378278 @default.
- W2783126905 cites W2057745517 @default.
- W2783126905 cites W2063490058 @default.
- W2783126905 cites W2064846318 @default.
- W2783126905 cites W2067212116 @default.
- W2783126905 cites W2069753640 @default.
- W2783126905 cites W2072866986 @default.
- W2783126905 cites W2085107912 @default.
- W2783126905 cites W2091956821 @default.
- W2783126905 cites W2092903823 @default.
- W2783126905 cites W2093083195 @default.
- W2783126905 cites W2102335249 @default.
- W2783126905 cites W2107328689 @default.
- W2783126905 cites W2117566194 @default.
- W2783126905 cites W2120113718 @default.
- W2783126905 cites W2122908273 @default.
- W2783126905 cites W2131839899 @default.
- W2783126905 cites W2133273834 @default.
- W2783126905 cites W2134489190 @default.
- W2783126905 cites W2141441464 @default.
- W2783126905 cites W2145849571 @default.
- W2783126905 cites W2150403537 @default.
- W2783126905 cites W2158112812 @default.
- W2783126905 cites W2165850423 @default.
- W2783126905 cites W2166193532 @default.
- W2783126905 cites W2171069521 @default.
- W2783126905 cites W2230948130 @default.
- W2783126905 cites W2297352394 @default.
- W2783126905 cites W2325250956 @default.
- W2783126905 cites W2344669468 @default.
- W2783126905 cites W2409364830 @default.
- W2783126905 cites W2599685052 @default.
- W2783126905 cites W2624910216 @default.
- W2783126905 doi "https://doi.org/10.1016/j.virol.2017.12.037" @default.
- W2783126905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29324360" @default.
- W2783126905 hasPublicationYear "2018" @default.
- W2783126905 type Work @default.
- W2783126905 sameAs 2783126905 @default.
- W2783126905 citedByCount "10" @default.
- W2783126905 countsByYear W27831269052018 @default.
- W2783126905 countsByYear W27831269052019 @default.
- W2783126905 countsByYear W27831269052020 @default.
- W2783126905 countsByYear W27831269052021 @default.
- W2783126905 crossrefType "journal-article" @default.
- W2783126905 hasAuthorship W2783126905A5000348178 @default.
- W2783126905 hasAuthorship W2783126905A5037862053 @default.
- W2783126905 hasAuthorship W2783126905A5041885929 @default.
- W2783126905 hasAuthorship W2783126905A5054463973 @default.
- W2783126905 hasAuthorship W2783126905A5071285237 @default.
- W2783126905 hasAuthorship W2783126905A5079898992 @default.
- W2783126905 hasAuthorship W2783126905A5086905248 @default.
- W2783126905 hasBestOaLocation W27831269051 @default.
- W2783126905 hasConcept C104317684 @default.
- W2783126905 hasConcept C139807058 @default.
- W2783126905 hasConcept C159047783 @default.
- W2783126905 hasConcept C169760540 @default.
- W2783126905 hasConcept C193252679 @default.
- W2783126905 hasConcept C2522874641 @default.
- W2783126905 hasConcept C2778692840 @default.
- W2783126905 hasConcept C3019819676 @default.
- W2783126905 hasConcept C44465124 @default.
- W2783126905 hasConcept C519248777 @default.
- W2783126905 hasConcept C54355233 @default.
- W2783126905 hasConcept C78458016 @default.
- W2783126905 hasConcept C86803240 @default.
- W2783126905 hasConcept C90132467 @default.
- W2783126905 hasConcept C90856448 @default.
- W2783126905 hasConceptScore W2783126905C104317684 @default.
- W2783126905 hasConceptScore W2783126905C139807058 @default.
- W2783126905 hasConceptScore W2783126905C159047783 @default.