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• W2783154848 abstract "// Jing Qian 1, 2, * , Defa Zhang 1, 2, * , Liying Gao 1, 2 , Aiping Yu 1, 2 , Chunting Qiu 1 , Lei Li 1 , Fangfang Yu 1 , Yue Wu 1 , Wei You 1, 2 , Yanyun Guo 1 , Jinghua Wang 3, 4, 5 , Xianjia Ning 3, 4, 5 , Wei Lu 1 and Ping Ma 1, 2 1 Department of Infectious Disease, Tianjin Second People’s Hospital, Tianjin 300192, China 2 Association of Tianjin STD and AIDS Prevention and Treatment, Tianjin 300050,China 3 Center of Epidemiology and Department of Neurology, Tianjin Medical University General Hospital, Tianjin 300052, China 4 Tianjin Neurological Institute, Key Laboratory of Post-Neuroinjury Neuro-repair and Regeneration in Central Nervous System, Ministry of Education and Tianjin City, Tianjin 300052, China 5 Department of Epidemiology, Tianjin Neurological Institute, Tianjin 300052, China * These authors contributed equally to this work Correspondence to: Ping Ma, email: mapingtianjin@163.com Wei Lu, email: luweidr@126.com Keywords: AIDS; epidemiology; trends; CD4 cell count; china Received: September 22, 2017      Accepted: December 05, 2017      Published: January 12, 2018 ABSTRACT The purpose of this study was to assess trends in CD4 cell counts among patients with AIDS living in Tianjin, China. All patients with AIDS who were registered in Tianjin from 2005 to 2016 were recruited to this study. Information on demographic characteristics and clinical features was recorded. Mean CD4 cell counts and the frequency of CD4 cell counts <200 were assessed by age, transmission route, and education level. Men accounted for 93.6% of cases (2867 cases), and women accounted for 6.4% (195 cases). The median CD4 cell counts significantly increased for each age group over the 12-yearstudy period overall; in particular, median counts increased by 67.4% in patients aged <25 years. Similar trends were found in patients infected through homosexual transmission and those with an education level of ≥13 years. Compared to that in 2005–2010, the prevalence of low CD4 levels (<200) was significantly decreased in 2016, especially for patients aged 25–29 years, those infected through homosexual transmission, and those with ≥13 years of education. These findings suggest that the burden of AIDS will continue to increase in Tianjin. It is crucial to begin managing AIDS patients who still have high CD4 cell counts in order to ensure effective therapy. At the same time, education of high-risk populations should begin in high school." @default.
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• W2783154848 date "2018-01-12" @default.
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• W2783154848 title "Temporal trends in CD4-positive T-cell counts among AIDS patients in Tianjin, China: 2005–2016" @default.
• W2783154848 doi "https://doi.org/10.18632/oncotarget.24195" @default.
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