Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783155425> ?p ?o ?g. }
- W2783155425 endingPage "71" @default.
- W2783155425 startingPage "65" @default.
- W2783155425 abstract "MicroRNAs (miRNAs) are important regulators of physiologic and pathologic conditions of the heart. Animal models of heart diseases have shown that miRNAs may contribute to the development of arrhythmias. However, little is known about the expression of muscle- and cardiac-specific miRNAs in patients with myocardial infarction (MI) who have developed ventricular fibrillation (VF). Our study included 47 patients who had died from myocardial infarction (MI), 23 with clinically proven VF and 24 without VF. Autopsy samples of infarcted tissue and remote myocardium were available (n = 94). Heart tissue from 8 healthy trauma victims was included as control. Expression of miR-1, miR-133a/b and miR-208 was analyzed using real-time PCR (qPCR). In patients with MI with VF, we observed down-regulation of miR-133a/b, and this down-regulation was even stronger 2-7 days after MI. miR-208 was up-regulated in remote myocardium irrespective of the presence of VF. Deregulation of miR-1 and miR-208 was not related to the presence of VF. Our results suggest that down-regulation of miR-133a/b might contribute to the development of VF in patients with MI. However, up-regulation of miR-1 and miR-208 in remote myocardium might play a role in cardiac remodeling after MI, at least to certain degree." @default.
- W2783155425 created "2018-01-26" @default.
- W2783155425 creator A5006896055 @default.
- W2783155425 creator A5018586125 @default.
- W2783155425 creator A5037858126 @default.
- W2783155425 creator A5048805964 @default.
- W2783155425 creator A5077674321 @default.
- W2783155425 date "2018-03-01" @default.
- W2783155425 modified "2023-10-18" @default.
- W2783155425 title "Down-regulation of miR-133a/b in patients with myocardial infarction correlates with the presence of ventricular fibrillation" @default.
- W2783155425 cites W1828283085 @default.
- W2783155425 cites W1884338871 @default.
- W2783155425 cites W1963881476 @default.
- W2783155425 cites W1974068616 @default.
- W2783155425 cites W1990198183 @default.
- W2783155425 cites W1992389076 @default.
- W2783155425 cites W1993834583 @default.
- W2783155425 cites W2014899966 @default.
- W2783155425 cites W2023721398 @default.
- W2783155425 cites W2030588498 @default.
- W2783155425 cites W2048358092 @default.
- W2783155425 cites W2050448117 @default.
- W2783155425 cites W2058158664 @default.
- W2783155425 cites W2059002457 @default.
- W2783155425 cites W2061226821 @default.
- W2783155425 cites W2069569950 @default.
- W2783155425 cites W2073065225 @default.
- W2783155425 cites W2079030743 @default.
- W2783155425 cites W2104802504 @default.
- W2783155425 cites W2107277218 @default.
- W2783155425 cites W2107320342 @default.
- W2783155425 cites W2118105142 @default.
- W2783155425 cites W2137132557 @default.
- W2783155425 cites W2141927767 @default.
- W2783155425 cites W2165869851 @default.
- W2783155425 cites W2170341042 @default.
- W2783155425 cites W2239883203 @default.
- W2783155425 cites W2289647240 @default.
- W2783155425 cites W2318083254 @default.
- W2783155425 cites W2341030489 @default.
- W2783155425 cites W2484043463 @default.
- W2783155425 doi "https://doi.org/10.1016/j.biopha.2018.01.019" @default.
- W2783155425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29324314" @default.
- W2783155425 hasPublicationYear "2018" @default.
- W2783155425 type Work @default.
- W2783155425 sameAs 2783155425 @default.
- W2783155425 citedByCount "21" @default.
- W2783155425 countsByYear W27831554252019 @default.
- W2783155425 countsByYear W27831554252020 @default.
- W2783155425 countsByYear W27831554252021 @default.
- W2783155425 countsByYear W27831554252022 @default.
- W2783155425 countsByYear W27831554252023 @default.
- W2783155425 crossrefType "journal-article" @default.
- W2783155425 hasAuthorship W2783155425A5006896055 @default.
- W2783155425 hasAuthorship W2783155425A5018586125 @default.
- W2783155425 hasAuthorship W2783155425A5037858126 @default.
- W2783155425 hasAuthorship W2783155425A5048805964 @default.
- W2783155425 hasAuthorship W2783155425A5077674321 @default.
- W2783155425 hasConcept C104317684 @default.
- W2783155425 hasConcept C126322002 @default.
- W2783155425 hasConcept C145059251 @default.
- W2783155425 hasConcept C164705383 @default.
- W2783155425 hasConcept C2777798775 @default.
- W2783155425 hasConcept C2779504383 @default.
- W2783155425 hasConcept C2781005686 @default.
- W2783155425 hasConcept C500558357 @default.
- W2783155425 hasConcept C55493867 @default.
- W2783155425 hasConcept C71924100 @default.
- W2783155425 hasConcept C86803240 @default.
- W2783155425 hasConceptScore W2783155425C104317684 @default.
- W2783155425 hasConceptScore W2783155425C126322002 @default.
- W2783155425 hasConceptScore W2783155425C145059251 @default.
- W2783155425 hasConceptScore W2783155425C164705383 @default.
- W2783155425 hasConceptScore W2783155425C2777798775 @default.
- W2783155425 hasConceptScore W2783155425C2779504383 @default.
- W2783155425 hasConceptScore W2783155425C2781005686 @default.
- W2783155425 hasConceptScore W2783155425C500558357 @default.
- W2783155425 hasConceptScore W2783155425C55493867 @default.
- W2783155425 hasConceptScore W2783155425C71924100 @default.
- W2783155425 hasConceptScore W2783155425C86803240 @default.
- W2783155425 hasLocation W27831554251 @default.
- W2783155425 hasLocation W27831554252 @default.
- W2783155425 hasOpenAccess W2783155425 @default.
- W2783155425 hasPrimaryLocation W27831554251 @default.
- W2783155425 hasRelatedWork W1963833110 @default.
- W2783155425 hasRelatedWork W1965887404 @default.
- W2783155425 hasRelatedWork W2041903483 @default.
- W2783155425 hasRelatedWork W2049397185 @default.
- W2783155425 hasRelatedWork W2080954990 @default.
- W2783155425 hasRelatedWork W2366831242 @default.
- W2783155425 hasRelatedWork W2399063111 @default.
- W2783155425 hasRelatedWork W2402109933 @default.
- W2783155425 hasRelatedWork W2465760590 @default.
- W2783155425 hasRelatedWork W2752120457 @default.
- W2783155425 hasVolume "99" @default.
- W2783155425 isParatext "false" @default.
- W2783155425 isRetracted "false" @default.
- W2783155425 magId "2783155425" @default.