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• W2783158738 abstract "RESUMEN Introducción y objetivos: Evaluar prospectivamente la asociación entre el consumo de huevo y el riesgo de dislipidemia en una cohorte mediterránea.Métodos: Se siguieron a 13.104 graduados universitarios españoles durante un período medio de 8 años. La dieta se evaluó al inicio utilizando un cuestionario semicuantitativo de frecuencia de consumo de alimentos repetidamente validado. Las concentraciones sanguíneas de colesterol total, lipoproteínas de alta densidad (HDL-c) y triglicéridos autoreferidas fueron evaluadas según categorías de consumo de huevo tras 6 y 8 años de seguimiento. También se evaluó la asociación entre el consumo basal de huevo y la incidencia de hipercolesterolemia, concentraciones bajas de HDL-c e hipertrigliceridemia durante el seguimiento.Resultados: Se observó una asociación entre los niveles intermedios de consumo de huevo (2-4 unidades/semana frente a <1 unidad/semana) y menor riesgo de hipertrigliceridemia con OR = 0,71 (intervalo de confianza del 95% [IC]: 0,54 a 0,93, p <0,05) en el modelo de ajustado. Tras 8 años de seguimiento, encontramos una asociación entre un mayor consumo de huevo y menores niveles de HDL-c (p tendencia lineal= 0,02) con una diferencia ajustada de -4,01mg/dl (-7,42 a -0,61) para >4 vs. <1 unidades/semana. Se encontraron menores concentraciones de triglicéridos en las tres categorías superiores de consumo de huevo en comparación con la inferior con resultados significativos para algunas de estas categorías después de 6 y 8 años de seguimiento.Conclusiones: Un mayor consumo de huevo no se asocia con niveles anormales de colesterol total o triglicéridos; Se encontró una asociación inversa con HDL-c como variable cuantitativa solo en uno de nuestros análisis.Palabras clave: consumo de huevo, cohorte, colesterol, HDL-c, triglicéridos, dislipidemia. ABSTRACTIntroduction and objectives: Our aim was to prospectively evaluate the association between egg consumption and dyslipidemia in a Mediterranean cohort.Methods: We followed-up 13,104 Spanish university graduates for a mean period of 8 years. Dietary habits at baseline were assessed using a validated semi-quantitative 136-item food-frequency questionnaire. Self-reported blood concentrations of total cholesterol, high-density lipoproteins cholesterol (HDL-c) and triglycerides were evaluated according to categories of egg consumption after 6 and 8 years of follow-up. We also assessed the association between baseline egg consumption and the incidence of hypercholesterolemia, low HDL-c concentrations and hypertriglyceridemia during follow-up.Results: We observed a significant inverse association for intermediate levels of egg consumption (2 to 4 eggs/week vs. less than 1 egg/week) and hypertriglyceridemia with OR=0.71 (95% confidence interval [CI]: 0.54 to 0.93, p<0.05) in the multivariable-adjusted model. Using HDL-c values after 8-year follow-up, we found an association between higher egg consumption and lower HDL-c levels (p for trend = 0.02) with an adjusted difference of –4.01 mg/dl (–¬7.42 to –0.61) for >4 vs. <1 egg/week. Lower means of triglycerides were found in each of the three upper categories of egg consumption compared to the lowest category (<1 egg/week) with significant results for some of these categories both after 6 and 8 year follow-up.Conclusions: Our data do not support that higher egg consumption is associated with abnormal blood levels of total cholesterol or triglycerides; an inverse association with HDL-c as a quantitative variable was found in one of our analyses.Key words: egg consumption, cohort, cholesterol, HDL-c, triglycerides, dyslipidemia" @default.
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• W2783158738 date "2018-01-12" @default.
• W2783158738 modified "2023-10-17" @default.
• W2783158738 title "TITTLE: Egg consumption and dyslipidemia in a Mediterranean cohort. TÍTULO: Consumo de huevo y dislipidemia en una cohorte mediterránea." @default.
• W2783158738 cites W2898798907 @default.
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• W2783158738 doi "https://doi.org/10.20960/nh.1347" @default.
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• W2783158738 hasPublicationYear "2018" @default.
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