Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783162903> ?p ?o ?g. }
- W2783162903 endingPage "440" @default.
- W2783162903 startingPage "440" @default.
- W2783162903 abstract "Optical forces are used to aggregate plasmonic nanoparticles and create SERS-active hot spots in liquid. When biomolecules are added to the nanoparticles, high sensitivity SERS detection can be accomplished. Here, we pursue studies on Bovine Serum Albumin (BSA) detection, investigating the BSA-nanorod aggregations in a range from 100 µM to 50 nM by combining light scattering, plasmon resonance and SERS, and correlating the SERS signal with the concentration. Experimental data are fitted with a simple model describing the optical aggregation process. We show that BSA-nanorod complexes can be optically printed on non-functionalized glass surfaces, designing custom patterns stable with time. Furthermore, we demonstrate that this methodology can be used to detect catalase and hemoglobin, two Raman resonant biomolecules, at concentrations of 10 nM and 1 pM, respectively, i.e., well beyond the limit of detection of BSA. Finally, we show that nanorods functionalized with specific aptamers can be used to capture and detect Ochratoxin A, a fungal toxin found in food commodities and wine. This experiment represents the first step towards the addition of molecular specificity to this novel biosensor strategy." @default.
- W2783162903 created "2018-01-26" @default.
- W2783162903 creator A5019314047 @default.
- W2783162903 creator A5022494090 @default.
- W2783162903 creator A5037129646 @default.
- W2783162903 creator A5038460182 @default.
- W2783162903 creator A5041816967 @default.
- W2783162903 creator A5052001661 @default.
- W2783162903 creator A5055272471 @default.
- W2783162903 creator A5055849040 @default.
- W2783162903 creator A5062096714 @default.
- W2783162903 creator A5089477740 @default.
- W2783162903 date "2018-03-17" @default.
- W2783162903 modified "2023-10-17" @default.
- W2783162903 title "Optical Aggregation of Gold Nanoparticles for SERS Detection of Proteins and Toxins in Liquid Environment: Towards Ultrasensitive and Selective Detection" @default.
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