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- W2783163188 abstract "The literature review presents information on the role of gene polymorphism of vitamin D receptor in human pathology. According to modern data, vitamin D is a hormone which has numerous pleiotropic effects on the human body by binding to its specific receptors (VDR). These effects can greatly determine the role of vitamin D in the occurence and the course of a number of widespread diseases of a modern man, including infectious pathology, autoimmune diseases, neuropsychiatric disorders. Special importance is currently attached to the receptor gene of vitamin D, VDR, which is characterized by a genetic polymorphism that can determine the features of implementation of the biological effects of calcitriol in the human body. The article presents the review data supporting the contribution of certain single nucleotide polymorphisms of gene VDR in the formation of the pleiotropic effects of vitamin D and their clinical manifestations." @default.
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- W2783163188 date "2017-01-01" @default.
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- W2783163188 title "SIGNIFICANCE OF GENE POLYMORPHISM OF VITAMIN D RECEPTOR IN HUMAN PATHOLOGY" @default.
- W2783163188 doi "https://doi.org/10.21508/1027-4065-2017-62-6-23-28" @default.
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