Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783167333> ?p ?o ?g. }
- W2783167333 abstract "Impaired wound healing is a common and serious complication of diabetes mellitus causing an increased risk of infection and tissue damage. Chronic wounds associated with diabetes may be caused by peripheral neuropathy, vascular complications and alterations in immune function and contributes tonon-traumatic amputations. Consequently, therapeutic management of wounds in diabetes is centred on infection control and stimulating revascularization. This research will focus on the latter and investigate the effects of high glucose on endothelial function with a view of finding new strategies to improve wound healing in diabetes. This project identified the adenosine receptor subtypes in EA.hy926 endothelial cell lines that are involved in stimulating wound healing and determined whether their roles are affected inthe hyperglycaemic environment associated with diabetes. As caffeine is a non-selective antagonist of the adenosine receptors, this study also investigated the effects of acute and 48 hour chronic caffeine treatments on adenosine receptor populations and on wound closure and cell proliferation. Caffeine has a crucial role in wound healing through various mechanisms such as antioxidant activity or increasing the level of cyclic adenosine monophosphate (cAMP)." @default.
- W2783167333 created "2018-01-26" @default.
- W2783167333 creator A5085293412 @default.
- W2783167333 date "2017-01-01" @default.
- W2783167333 modified "2023-09-23" @default.
- W2783167333 title "Adenosine Receptors And Endothelial Cell Mediated Wound Healing" @default.
- W2783167333 cites W103956845 @default.
- W2783167333 cites W119602754 @default.
- W2783167333 cites W125070947 @default.
- W2783167333 cites W1496188050 @default.
- W2783167333 cites W1500939054 @default.
- W2783167333 cites W1501287464 @default.
- W2783167333 cites W1502387883 @default.
- W2783167333 cites W1505264265 @default.
- W2783167333 cites W1522803047 @default.
- W2783167333 cites W1530525374 @default.
- W2783167333 cites W1536236588 @default.
- W2783167333 cites W1545077229 @default.
- W2783167333 cites W1545295983 @default.
- W2783167333 cites W1557228442 @default.
- W2783167333 cites W1572670061 @default.
- W2783167333 cites W1575186397 @default.
- W2783167333 cites W1580283865 @default.
- W2783167333 cites W1581396422 @default.
- W2783167333 cites W1585401061 @default.
- W2783167333 cites W1599314299 @default.
- W2783167333 cites W1603286011 @default.
- W2783167333 cites W1631317414 @default.
- W2783167333 cites W163885078 @default.
- W2783167333 cites W171447041 @default.
- W2783167333 cites W172270857 @default.
- W2783167333 cites W173818528 @default.
- W2783167333 cites W1741335664 @default.
- W2783167333 cites W1864853792 @default.
- W2783167333 cites W1880309739 @default.
- W2783167333 cites W1916037137 @default.
- W2783167333 cites W1925252539 @default.
- W2783167333 cites W1928430680 @default.
- W2783167333 cites W1930453831 @default.
- W2783167333 cites W1931304520 @default.
- W2783167333 cites W1943804967 @default.
- W2783167333 cites W1944355206 @default.
- W2783167333 cites W1949832432 @default.
- W2783167333 cites W1965781264 @default.
- W2783167333 cites W1965876706 @default.
- W2783167333 cites W1966532557 @default.
- W2783167333 cites W1966657000 @default.
- W2783167333 cites W1968896256 @default.
- W2783167333 cites W1969448591 @default.
- W2783167333 cites W1969883571 @default.
- W2783167333 cites W1969967455 @default.
- W2783167333 cites W1970027494 @default.
- W2783167333 cites W1971653362 @default.
- W2783167333 cites W1972291807 @default.
- W2783167333 cites W1974256482 @default.
- W2783167333 cites W1975225567 @default.
- W2783167333 cites W1977498504 @default.
- W2783167333 cites W1977880024 @default.
- W2783167333 cites W1978593678 @default.
- W2783167333 cites W1980483140 @default.
- W2783167333 cites W1981396672 @default.
- W2783167333 cites W1983069528 @default.
- W2783167333 cites W1983223101 @default.
- W2783167333 cites W1983407850 @default.
- W2783167333 cites W1984534675 @default.
- W2783167333 cites W1984725901 @default.
- W2783167333 cites W1985407729 @default.
- W2783167333 cites W1985554019 @default.
- W2783167333 cites W1985984293 @default.
- W2783167333 cites W1987538164 @default.
- W2783167333 cites W1988578676 @default.
- W2783167333 cites W198863258 @default.
- W2783167333 cites W1988802022 @default.
- W2783167333 cites W1988948020 @default.
- W2783167333 cites W1989214210 @default.
- W2783167333 cites W1989514730 @default.
- W2783167333 cites W1990590605 @default.
- W2783167333 cites W1991267259 @default.
- W2783167333 cites W1994092198 @default.
- W2783167333 cites W1994365906 @default.
- W2783167333 cites W1994932989 @default.
- W2783167333 cites W1994970739 @default.
- W2783167333 cites W1995267188 @default.
- W2783167333 cites W1996808726 @default.
- W2783167333 cites W1996910230 @default.
- W2783167333 cites W1997168440 @default.
- W2783167333 cites W2000000541 @default.
- W2783167333 cites W2000104936 @default.
- W2783167333 cites W2001110103 @default.
- W2783167333 cites W2003483275 @default.
- W2783167333 cites W2003649034 @default.
- W2783167333 cites W2003805915 @default.
- W2783167333 cites W2006027198 @default.
- W2783167333 cites W2007127551 @default.
- W2783167333 cites W2007462827 @default.
- W2783167333 cites W2008823506 @default.
- W2783167333 cites W2010114986 @default.
- W2783167333 cites W2010158637 @default.
- W2783167333 cites W2012666355 @default.
- W2783167333 cites W2013324232 @default.