Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783175714> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2783175714 abstract "The physical and chemical stability of Ciprofloxacin I.V- MetronidazoleI.V and Ciprofloxacin-Metronidazole I.V admixture were individually determinedat 45oC, 25oC and 5oC. Ciprofloxacin and Metronidazole were quantified by usinga stability indicating first derivative UV spectrophotometric method (E.Vega et.al;2001The physical and chemical stability of Ciprofloxacin when admixed withPeritoneal Dialysis (PD) solution was determined at 45oC, 25oC and 5oC andquantified by using a stability indicating HPTLC method (Jan Krzek et.al; 2005)in addition to a microbiological assay using E.coli – NCIM 2911 as test organism.Decrease in drug concentration by more than 10% from initialconcentration (0 time) was considered unstable (chemical instability). Change inpH by more than 1 unit was considered unstable (physical instability) (NarineBaririan et.al, 2003).The drug solution was clear and colorless, but the pH decreased with time,though not to the extent of being considered physically unstable.First derivative UV spectrophotometric analysis indicated that 2mg/mlconcentration of Ciprofloxacin I.V when tested alone maintained adequatestability for 4 hours at 45oC, for 24 hours at 25oC and up to120 hours at 5oC.5mg/ml concentration of Metronidazole alone maintained adequate stability for 6hours at 45oC, for 24 hours at 25oC and up to 120 hours at 5oC and the I.Vadmixture of ciprofloxacin with metronidazole (1:2.5) was stable for less than 4hours at 45oC, for 24 hours at 25oC and up to 120 hours at 5oC.HPTLC analysis indicated that 400μg/ml concentration of ciprofloxacinI.V in peritoneal dialysis solution maintained adequate stability for 4 hours at45oC, for 24 hours at 25oC and up to 120 hours at 5oC. As per microbiologicalassay, Ciprofloxacin in peritoneal dialysis solution was stable up to the studyperiod of 6 hours at all the three temperatures." @default.
- W2783175714 created "2018-01-26" @default.
- W2783175714 creator A5081024650 @default.
- W2783175714 date "2008-01-01" @default.
- W2783175714 modified "2023-09-23" @default.
- W2783175714 title "Stability Studies on certain Parenteral Ciprofloxacin Admixtures using Stability Indicating Assay" @default.
- W2783175714 cites W1797114892 @default.
- W2783175714 cites W1975435875 @default.
- W2783175714 cites W1996092850 @default.
- W2783175714 cites W2013251450 @default.
- W2783175714 cites W2042109068 @default.
- W2783175714 cites W2170293710 @default.
- W2783175714 cites W2402885434 @default.
- W2783175714 hasPublicationYear "2008" @default.
- W2783175714 type Work @default.
- W2783175714 sameAs 2783175714 @default.
- W2783175714 citedByCount "0" @default.
- W2783175714 crossrefType "dissertation" @default.
- W2783175714 hasAuthorship W2783175714A5081024650 @default.
- W2783175714 hasConcept C106159729 @default.
- W2783175714 hasConcept C111771559 @default.
- W2783175714 hasConcept C162324750 @default.
- W2783175714 hasConcept C178790620 @default.
- W2783175714 hasConcept C185592680 @default.
- W2783175714 hasConcept C186399102 @default.
- W2783175714 hasConcept C2777396551 @default.
- W2783175714 hasConcept C2778512257 @default.
- W2783175714 hasConcept C2909954168 @default.
- W2783175714 hasConcept C31972630 @default.
- W2783175714 hasConcept C41008148 @default.
- W2783175714 hasConcept C43617362 @default.
- W2783175714 hasConcept C501593827 @default.
- W2783175714 hasConcept C55493867 @default.
- W2783175714 hasConceptScore W2783175714C106159729 @default.
- W2783175714 hasConceptScore W2783175714C111771559 @default.
- W2783175714 hasConceptScore W2783175714C162324750 @default.
- W2783175714 hasConceptScore W2783175714C178790620 @default.
- W2783175714 hasConceptScore W2783175714C185592680 @default.
- W2783175714 hasConceptScore W2783175714C186399102 @default.
- W2783175714 hasConceptScore W2783175714C2777396551 @default.
- W2783175714 hasConceptScore W2783175714C2778512257 @default.
- W2783175714 hasConceptScore W2783175714C2909954168 @default.
- W2783175714 hasConceptScore W2783175714C31972630 @default.
- W2783175714 hasConceptScore W2783175714C41008148 @default.
- W2783175714 hasConceptScore W2783175714C43617362 @default.
- W2783175714 hasConceptScore W2783175714C501593827 @default.
- W2783175714 hasConceptScore W2783175714C55493867 @default.
- W2783175714 hasLocation W27831757141 @default.
- W2783175714 hasOpenAccess W2783175714 @default.
- W2783175714 hasPrimaryLocation W27831757141 @default.
- W2783175714 hasRelatedWork W1762786544 @default.
- W2783175714 hasRelatedWork W1847909592 @default.
- W2783175714 hasRelatedWork W1855161688 @default.
- W2783175714 hasRelatedWork W195475106 @default.
- W2783175714 hasRelatedWork W2029786719 @default.
- W2783175714 hasRelatedWork W2336512679 @default.
- W2783175714 hasRelatedWork W2348004357 @default.
- W2783175714 hasRelatedWork W2352361521 @default.
- W2783175714 hasRelatedWork W2365681975 @default.
- W2783175714 hasRelatedWork W2401630646 @default.
- W2783175714 hasRelatedWork W2432721958 @default.
- W2783175714 hasRelatedWork W2611940220 @default.
- W2783175714 hasRelatedWork W2614631795 @default.
- W2783175714 hasRelatedWork W2802204849 @default.
- W2783175714 hasRelatedWork W2893226165 @default.
- W2783175714 hasRelatedWork W2947238955 @default.
- W2783175714 hasRelatedWork W3138857411 @default.
- W2783175714 hasRelatedWork W3139084470 @default.
- W2783175714 hasRelatedWork W788566281 @default.
- W2783175714 hasRelatedWork W2189240426 @default.
- W2783175714 isParatext "false" @default.
- W2783175714 isRetracted "false" @default.
- W2783175714 magId "2783175714" @default.
- W2783175714 workType "dissertation" @default.