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- W2783182199 abstract "This chapter describes the application of a computer simulation of trabecular surface remodeling (proposed in Chap. 8) for investigating the spatial and temporal changes in the trabecular structure caused by remodeling. Two model parameters, the threshold value of the lazy zone and the sensing distance of the mechanical environment, are introduced into the remodeling rate equation to express the sensitivity of bone cells to mechanical stimuli. A two-dimensional rectangular cancellous bone model under non-uniform compressive loads is constructed using pixel finite elements. A simulation result revealed that the trabecular structure underwent temporal and spatial changes depending on the loading condition. Sensing distance regulates the spatial distribution of the trabecular structure, while the threshold value of the lazy zone regulates the rate of structural changes in time. The results indicate that these model parameters are important in controlling the spatial and temporal regulation of the trabecular structure that depends on the sensitivities of bone cells to mechanical stimuli." @default.
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- W2783182199 date "2018-01-01" @default.
- W2783182199 modified "2023-09-27" @default.
- W2783182199 title "Spatial and Temporal Regulation of Cancellous Bone Structure by Trabecular Surface Remodeling" @default.
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- W2783182199 doi "https://doi.org/10.1007/978-4-431-56514-7_9" @default.
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