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- W2783183962 abstract "Metadichol, a novel nano emulsion of lipid alcohols, up regulates the expression of GULO gene in mouse at picogram levels. 3T3-L1 pre adipocyte cells were differentiated using differentiating media. Post differentiation, the cells were treated with different concentrations of Metadichol for 24 hours and untreated cells served as control. Whole RNA was isolated after the treatment period and semi-quantitative reverse transcription PCR was run with GULO gene specific primer to obtain cDNA. Relative gene expression of GULO was determined by analysis of GULO gene amplicons using image J software. The GULO gene expression in the treated cells was up regulated fourfold relative to basal level of untreated cells.. Relative gene expression at concentrations 1 μg/ml, 100 ng/ml, 1 ng/ml, 100 pg/ml, 1 pg/ml was found to be 2.11, 2.64, 2.96, 3.96, 3.25 fold compared to control." @default.
- W2783183962 created "2018-01-26" @default.
- W2783183962 creator A5086897801 @default.
- W2783183962 date "2017-01-01" @default.
- W2783183962 modified "2023-10-10" @default.
- W2783183962 title "Metadichol®, Vitamin C and GULO Gene Expression in Mouse Adipocytes" @default.
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- W2783183962 doi "https://doi.org/10.4172/0974-8369.1000426" @default.
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