Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783190320> ?p ?o ?g. }
- W2783190320 abstract "To optimize the design of nanoparticles for diagnosis or therapy of vascular diseases, it is mandatory to characterize the determinants of nano-bio interactions in vascular lesions.Using ex vivo and in vivo microscopy, we analyzed the interactive behavior of quantum dots with different surface functionalizations in atherosclerotic lesions of ApoE-deficient mice.We demonstrate that quantum dots with different surface functionalizations exhibit specific interactive behaviors with distinct molecular and cellular components of the injured vessel wall. Moreover, we show a role for fibrinogen in the regulation of the spatio-temporal interaction dynamics in atherosclerotic lesions.Our findings emphasize the relevance of surface chemistry-driven nano-bio interactions on the differential in vivo behavior of nanoparticles in diseased tissue." @default.
- W2783190320 created "2018-01-26" @default.
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- W2783190320 date "2018-03-01" @default.
- W2783190320 modified "2023-09-27" @default.
- W2783190320 title "The surface chemistry determines the spatio–temporal interaction dynamics of quantum dots in atherosclerotic lesions" @default.
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- W2783190320 doi "https://doi.org/10.2217/nnm-2017-0350" @default.
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