FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783205241> ?p ?o ?g. }

• W2783205241 endingPage "168" @default.
• W2783205241 startingPage "168" @default.
• W2783205241 abstract "Honey-processed Astragalus is a dosage form of Radix Astragalus mixed with honey by a traditional Chinese medicine processing method which strengthens the tonic effect. Astragalus polysaccharide (APS), perform its immunomodulatory effects by relying on the tonic effect of Radix Astragalus, therefore, the improved pharmacological activity of honey-processed Astragalus polysaccharide (HAPS) might be due to structural changes during processing. The molecular weights of HAPS and APS were 1,695,788 Da, 2,047,756 Da, respectively, as determined by high performance gel filtration chromatography combined with evaporative light scattering detection (HPGFC-ELSD). The monosaccharide composition was determined by ultra-performance liquid chromatogram quadrupole time-of-flight mass spectrometry (UPLC/ESI-Q-TOF-MS) after pre-column derivatization with 1-phenyl-3-methyl-5-pyrazolone (PMP). The results showed that the essential components were mannose, glucose, xylose, arabinose, glucuronic acid and rhamnose, is molar ratios of 0.06:28.34:0.58:0.24:0.33:0.21 and 0.27:12.83:1.63:0.71:1.04:0.56, respectively. FT-IR and NMR analysis of HAPS results showed the presence of uronic acid and acetyl groups. The anti-inflammatory activities of HAPS were more effective than those of APS according to the NO contents and the expression of IFN-γ, IL-1β, IL-22 and TNF-α in lipopolysaccharide (LPS)-induced RAW264.7 cells. This findings suggest that the anti-inflammatory and bioactivity improvement might be associated with molecular structure changes, bearing on the potential immunomodulatory action." @default.
• W2783205241 created "2018-01-26" @default.
• W2783205241 creator A5008598538 @default.
• W2783205241 creator A5033431973 @default.
• W2783205241 creator A5055124372 @default.
• W2783205241 creator A5055748108 @default.
• W2783205241 creator A5065136372 @default.
• W2783205241 creator A5077529251 @default.
• W2783205241 creator A5086732885 @default.
• W2783205241 date "2018-01-15" @default.
• W2783205241 modified "2023-10-01" @default.
• W2783205241 title "Structure Characterization of Honey-Processed Astragalus Polysaccharides and Its Anti-Inflammatory Activity In Vitro" @default.
• W2783205241 cites W1129153417 @default.
• W2783205241 cites W1671779243 @default.
• W2783205241 cites W1970358799 @default.
• W2783205241 cites W1996158471 @default.
• W2783205241 cites W2004025099 @default.
• W2783205241 cites W2013093324 @default.
• W2783205241 cites W2027103405 @default.
• W2783205241 cites W2034126263 @default.
• W2783205241 cites W2043543912 @default.
• W2783205241 cites W2048417035 @default.
• W2783205241 cites W2056177287 @default.
• W2783205241 cites W2086642732 @default.
• W2783205241 cites W2100754941 @default.
• W2783205241 cites W2114918609 @default.
• W2783205241 cites W2136521254 @default.
• W2783205241 cites W2173309320 @default.
• W2783205241 cites W2214061434 @default.
• W2783205241 cites W2469512964 @default.
• W2783205241 cites W2531069153 @default.
• W2783205241 cites W2586945937 @default.
• W2783205241 cites W2596637810 @default.
• W2783205241 doi "https://doi.org/10.3390/molecules23010168" @default.
• W2783205241 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6017495" @default.
• W2783205241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29342936" @default.
• W2783205241 hasPublicationYear "2018" @default.
• W2783205241 type Work @default.
• W2783205241 sameAs 2783205241 @default.
• W2783205241 citedByCount "41" @default.
• W2783205241 countsByYear W27832052412018 @default.
• W2783205241 countsByYear W27832052412019 @default.
• W2783205241 countsByYear W27832052412020 @default.
• W2783205241 countsByYear W27832052412021 @default.
• W2783205241 countsByYear W27832052412022 @default.
• W2783205241 countsByYear W27832052412023 @default.
• W2783205241 crossrefType "journal-article" @default.
• W2783205241 hasAuthorship W2783205241A5008598538 @default.
• W2783205241 hasAuthorship W2783205241A5033431973 @default.
• W2783205241 hasAuthorship W2783205241A5055124372 @default.
• W2783205241 hasAuthorship W2783205241A5055748108 @default.
• W2783205241 hasAuthorship W2783205241A5065136372 @default.
• W2783205241 hasAuthorship W2783205241A5077529251 @default.
• W2783205241 hasAuthorship W2783205241A5086732885 @default.
• W2783205241 hasBestOaLocation W27832052411 @default.
• W2783205241 hasConcept C100544194 @default.
• W2783205241 hasConcept C100817775 @default.
• W2783205241 hasConcept C110084920 @default.
• W2783205241 hasConcept C118859902 @default.
• W2783205241 hasConcept C142724271 @default.
• W2783205241 hasConcept C162356407 @default.
• W2783205241 hasConcept C179998833 @default.
• W2783205241 hasConcept C181199279 @default.
• W2783205241 hasConcept C185592680 @default.
• W2783205241 hasConcept C188947578 @default.
• W2783205241 hasConcept C193363816 @default.
• W2783205241 hasConcept C202751555 @default.
• W2783205241 hasConcept C204787440 @default.
• W2783205241 hasConcept C2776084176 @default.
• W2783205241 hasConcept C2776648616 @default.
• W2783205241 hasConcept C2779213145 @default.
• W2783205241 hasConcept C2780294150 @default.
• W2783205241 hasConcept C2780798337 @default.
• W2783205241 hasConcept C43617362 @default.
• W2783205241 hasConcept C55493867 @default.
• W2783205241 hasConcept C71924100 @default.
• W2783205241 hasConceptScore W2783205241C100544194 @default.
• W2783205241 hasConceptScore W2783205241C100817775 @default.
• W2783205241 hasConceptScore W2783205241C110084920 @default.
• W2783205241 hasConceptScore W2783205241C118859902 @default.
• W2783205241 hasConceptScore W2783205241C142724271 @default.
• W2783205241 hasConceptScore W2783205241C162356407 @default.
• W2783205241 hasConceptScore W2783205241C179998833 @default.
• W2783205241 hasConceptScore W2783205241C181199279 @default.
• W2783205241 hasConceptScore W2783205241C185592680 @default.
• W2783205241 hasConceptScore W2783205241C188947578 @default.
• W2783205241 hasConceptScore W2783205241C193363816 @default.
• W2783205241 hasConceptScore W2783205241C202751555 @default.
• W2783205241 hasConceptScore W2783205241C204787440 @default.
• W2783205241 hasConceptScore W2783205241C2776084176 @default.
• W2783205241 hasConceptScore W2783205241C2776648616 @default.
• W2783205241 hasConceptScore W2783205241C2779213145 @default.
• W2783205241 hasConceptScore W2783205241C2780294150 @default.
• W2783205241 hasConceptScore W2783205241C2780798337 @default.
• W2783205241 hasConceptScore W2783205241C43617362 @default.
• W2783205241 hasConceptScore W2783205241C55493867 @default.
• W2783205241 hasConceptScore W2783205241C71924100 @default.
• W2783205241 hasIssue "1" @default.

• next