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- W2783233321 abstract "Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient. For orally taken drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to appreciate that a tablet contains a variety of other substances apart from the drug itself, and studies have to be carried out to ensure that the drug is compatible with these other substances. A fixed dose combination of tablet formulation of Artemether and Lumefantrine was successfully developed that has in-vitro drug release characteristics same as compared to the Conventional Coartem, Novartis Ltd., product. Moreover the developed product is morebetter with regards to formulation components and processing aspects. Benchmark for treatment of acute uncomplicated malaria caused by Plasmodium falciparum, including malaria acquired in chloroquine-resistant areas . If the formulation technology is transferred for production of Artemether and Lumefantrine tablets in large scale then it will be cost effective in India and international market. Utilization of total amount of drug can be improved through this fixed dose combination technique. Hence the cost of treatment can be reduced as well as patient care time" @default.
- W2783233321 created "2018-01-26" @default.
- W2783233321 creator A5019193173 @default.
- W2783233321 date "2013-04-01" @default.
- W2783233321 modified "2023-09-26" @default.
- W2783233321 title "Formulation and Development of Fixed Dose Combination of Artemether and Lumefantrine Tablets for the Treatment of Malaria." @default.
- W2783233321 hasPublicationYear "2013" @default.
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