FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783234686> ?p ?o ?g. }

• W2783234686 abstract "Metformin, the drug of choice in the treatment of type 2 diabetes mellitus (DM2), in addition to aspirin (ASA), the drug prescribed for cardioprotection of diabetic and non‑diabetic patients, have an inhibitory effect on cancer cell survival. The present population‑based study conducted in the province of Trieste (Italy), aimed to investigate the prevalence of DM2 in patients with colorectal adenocarcinoma (CRC) and survival for CRC in diabetic and nondiabetic patients. All permanent residents diagnosed with a CRC between 2004 and 2007 were ascertained through the regional health information system. CRC‑specific and relative survival probabilities were computed for each group of patients defined by CRC stage, presence or absence of DM2 treated with metformin, and presence or absence of daily ASA therapy. A total of 515 CRC patients without DM2 and 156 with DM2 treated with metformin were enrolled in the study. At the time of CRC diagnosis, 71 (14%) nondiabetic and 39 (25%) diabetic patients were taking ASA daily. The five‑year relative survival for stage III CRC was 101% [95% confidence interval (CI)=76‑126] in the 18 patients with DM2 treated with metformin and ASA, 55% (95% CI=31‑78) in the 23 without DM2 treated with ASA, 55% (95% CI=45‑65) in the 150 without DM2 not taking ASA, and 29% (95% CI=13‑45) in the 43 with DM2 treated with metformin, however not with ASA. The findings support the hypothesis of a possible inhibitory effect of metformin and ASA on CRC cells. Randomized controlled trials are required to verify this hypothesis." @default.
• W2783234686 created "2018-01-26" @default.
• W2783234686 creator A5029888685 @default.
• W2783234686 creator A5036849913 @default.
• W2783234686 creator A5045520592 @default.
• W2783234686 creator A5051191127 @default.
• W2783234686 creator A5052387567 @default.
• W2783234686 creator A5056546260 @default.
• W2783234686 creator A5057717851 @default.
• W2783234686 creator A5066304298 @default.
• W2783234686 date "2018-01-11" @default.
• W2783234686 modified "2023-10-16" @default.
• W2783234686 title "Metformin and aspirin treatment could lead to an improved survival rate for Type 2 diabetic patients with stage II and III colorectal adenocarcinoma relative to non-diabetic patients" @default.
• W2783234686 cites W1526272892 @default.
• W2783234686 cites W1585462082 @default.
• W2783234686 cites W1601876536 @default.
• W2783234686 cites W1986491294 @default.
• W2783234686 cites W2022805973 @default.
• W2783234686 cites W2032157537 @default.
• W2783234686 cites W2042292082 @default.
• W2783234686 cites W2043854938 @default.
• W2783234686 cites W2044461008 @default.
• W2783234686 cites W2048750730 @default.
• W2783234686 cites W2059526179 @default.
• W2783234686 cites W2063130014 @default.
• W2783234686 cites W2065434214 @default.
• W2783234686 cites W2075294845 @default.
• W2783234686 cites W2098098439 @default.
• W2783234686 cites W2103955948 @default.
• W2783234686 cites W2104005551 @default.
• W2783234686 cites W2107408187 @default.
• W2783234686 cites W2111304515 @default.
• W2783234686 cites W2112446953 @default.
• W2783234686 cites W2113389249 @default.
• W2783234686 cites W2139923324 @default.
• W2783234686 cites W2142277448 @default.
• W2783234686 cites W2156302844 @default.
• W2783234686 cites W2280619653 @default.
• W2783234686 cites W2338743383 @default.
• W2783234686 cites W2346529877 @default.
• W2783234686 cites W2429298507 @default.
• W2783234686 cites W2536830316 @default.
• W2783234686 cites W2558814374 @default.
• W2783234686 cites W2572228400 @default.
• W2783234686 cites W2603697780 @default.
• W2783234686 cites W2724744060 @default.
• W2783234686 cites W2756380574 @default.
• W2783234686 cites W4240986128 @default.
• W2783234686 cites W69342848 @default.
• W2783234686 doi "https://doi.org/10.3892/mco.2018.1554" @default.
• W2783234686 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5795555" @default.
• W2783234686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29456855" @default.
• W2783234686 hasPublicationYear "2018" @default.
• W2783234686 type Work @default.
• W2783234686 sameAs 2783234686 @default.
• W2783234686 citedByCount "5" @default.
• W2783234686 countsByYear W27832346862018 @default.
• W2783234686 countsByYear W27832346862019 @default.
• W2783234686 countsByYear W27832346862020 @default.
• W2783234686 countsByYear W27832346862023 @default.
• W2783234686 crossrefType "journal-article" @default.
• W2783234686 hasAuthorship W2783234686A5029888685 @default.
• W2783234686 hasAuthorship W2783234686A5036849913 @default.
• W2783234686 hasAuthorship W2783234686A5045520592 @default.
• W2783234686 hasAuthorship W2783234686A5051191127 @default.
• W2783234686 hasAuthorship W2783234686A5052387567 @default.
• W2783234686 hasAuthorship W2783234686A5056546260 @default.
• W2783234686 hasAuthorship W2783234686A5057717851 @default.
• W2783234686 hasAuthorship W2783234686A5066304298 @default.
• W2783234686 hasBestOaLocation W27832346861 @default.
• W2783234686 hasConcept C121608353 @default.
• W2783234686 hasConcept C126322002 @default.
• W2783234686 hasConcept C134018914 @default.
• W2783234686 hasConcept C2777180221 @default.
• W2783234686 hasConcept C2777628954 @default.
• W2783234686 hasConcept C2779306644 @default.
• W2783234686 hasConcept C2780323712 @default.
• W2783234686 hasConcept C2908647359 @default.
• W2783234686 hasConcept C2910068830 @default.
• W2783234686 hasConcept C44249647 @default.
• W2783234686 hasConcept C526805850 @default.
• W2783234686 hasConcept C555293320 @default.
• W2783234686 hasConcept C71924100 @default.
• W2783234686 hasConcept C82789193 @default.
• W2783234686 hasConcept C90924648 @default.
• W2783234686 hasConcept C99454951 @default.
• W2783234686 hasConceptScore W2783234686C121608353 @default.
• W2783234686 hasConceptScore W2783234686C126322002 @default.
• W2783234686 hasConceptScore W2783234686C134018914 @default.
• W2783234686 hasConceptScore W2783234686C2777180221 @default.
• W2783234686 hasConceptScore W2783234686C2777628954 @default.
• W2783234686 hasConceptScore W2783234686C2779306644 @default.
• W2783234686 hasConceptScore W2783234686C2780323712 @default.
• W2783234686 hasConceptScore W2783234686C2908647359 @default.
• W2783234686 hasConceptScore W2783234686C2910068830 @default.
• W2783234686 hasConceptScore W2783234686C44249647 @default.
• W2783234686 hasConceptScore W2783234686C526805850 @default.
• W2783234686 hasConceptScore W2783234686C555293320 @default.
• W2783234686 hasConceptScore W2783234686C71924100 @default.
• W2783234686 hasConceptScore W2783234686C82789193 @default.

• next