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- W2783234698 abstract "Neuromodulation is a ubiquitous feature of neural systems, allowing flexible, context specific control over network dynamics. Neuromodulation was first described in invertebrate motor systems and early work established a basic dichotomy for neuromodulation as having either an intrinsic origin (i.e. neurons that participate in network coding) or an extrinsic origin (i.e. neurons from independent networks). In this conceptual dichotomy, intrinsic sources of neuromodulation provide a “memory” by adjusting network dynamics based upon previous and ongoing activation of the network itself, while extrinsic neuromodulators provide the context of ongoing activity of other neural networks. Although this dichotomy has been thoroughly considered in motor systems, it has received far less attention in sensory systems. In this review, we discuss intrinsic and extrinsic modulation in the context of olfactory processing in invertebrate and vertebrate model systems. We begin by discussing presynaptic modulation of olfactory sensory neurons by local interneurons as a mechanism for gain control based on ongoing network activation. We then discuss the cell-class specific effects of serotonergic centrifugal neurons on olfactory processing. Finally, we briefly discuss the integration of intrinsic and extrinsic neuromodulation (metamodulation) as an effective mechanism for exerting global control over olfactory network dynamics. The heterogeneous nature of neuromodulation is a recurring theme throughout this review as the effects of both intrinsic and extrinsic modulation are generally non-uniform." @default.
- W2783234698 created "2018-01-26" @default.
- W2783234698 creator A5034821942 @default.
- W2783234698 creator A5083927492 @default.
- W2783234698 date "2018-01-09" @default.
- W2783234698 modified "2023-10-16" @default.
- W2783234698 title "Intrinsic and Extrinsic Neuromodulation of Olfactory Processing" @default.
- W2783234698 cites W135333518 @default.
- W2783234698 cites W1482096555 @default.
- W2783234698 cites W1484628435 @default.
- W2783234698 cites W1540637944 @default.
- W2783234698 cites W1542613299 @default.
- W2783234698 cites W1565257873 @default.
- W2783234698 cites W1580513152 @default.
- W2783234698 cites W1590835214 @default.
- W2783234698 cites W1677270978 @default.
- W2783234698 cites W1706830489 @default.
- W2783234698 cites W1753924902 @default.
- W2783234698 cites W1795810020 @default.
- W2783234698 cites W1829022302 @default.
- W2783234698 cites W1842929407 @default.
- W2783234698 cites W1865560007 @default.
- W2783234698 cites W1885843324 @default.
- W2783234698 cites W1946561635 @default.
- W2783234698 cites W1965141451 @default.
- W2783234698 cites W1965953864 @default.
- W2783234698 cites W1968880709 @default.
- W2783234698 cites W1969229186 @default.
- W2783234698 cites W1969591864 @default.
- W2783234698 cites W1972201383 @default.
- W2783234698 cites W1974148644 @default.
- W2783234698 cites W1974167708 @default.
- W2783234698 cites W1976636888 @default.
- W2783234698 cites W1977057715 @default.
- W2783234698 cites W1978033464 @default.
- W2783234698 cites W1979540477 @default.
- W2783234698 cites W1979554794 @default.
- W2783234698 cites W1981922832 @default.
- W2783234698 cites W1983939877 @default.
- W2783234698 cites W1984001074 @default.
- W2783234698 cites W1985744851 @default.
- W2783234698 cites W1986908558 @default.
- W2783234698 cites W1989597268 @default.
- W2783234698 cites W1989753378 @default.
- W2783234698 cites W1991974510 @default.
- W2783234698 cites W1992436705 @default.
- W2783234698 cites W1994992542 @default.
- W2783234698 cites W1995018068 @default.
- W2783234698 cites W1999133078 @default.
- W2783234698 cites W2000714136 @default.
- W2783234698 cites W2001867246 @default.
- W2783234698 cites W2002032433 @default.
- W2783234698 cites W2002411888 @default.
- W2783234698 cites W2002577038 @default.
- W2783234698 cites W2003324942 @default.
- W2783234698 cites W2003451378 @default.
- W2783234698 cites W2003534271 @default.
- W2783234698 cites W2004001620 @default.
- W2783234698 cites W2004259321 @default.
- W2783234698 cites W2005453809 @default.
- W2783234698 cites W2006902177 @default.
- W2783234698 cites W2007786915 @default.
- W2783234698 cites W2009409369 @default.
- W2783234698 cites W2010915373 @default.
- W2783234698 cites W2011669984 @default.
- W2783234698 cites W2012107116 @default.
- W2783234698 cites W2013425429 @default.
- W2783234698 cites W2013827619 @default.
- W2783234698 cites W2013832967 @default.
- W2783234698 cites W2014590358 @default.
- W2783234698 cites W2017547033 @default.
- W2783234698 cites W2018419775 @default.
- W2783234698 cites W2020538537 @default.
- W2783234698 cites W2020578912 @default.
- W2783234698 cites W2020864408 @default.
- W2783234698 cites W2021132254 @default.
- W2783234698 cites W2022016583 @default.
- W2783234698 cites W2022790467 @default.
- W2783234698 cites W2022795707 @default.
- W2783234698 cites W2024325136 @default.
- W2783234698 cites W2026533939 @default.
- W2783234698 cites W2028041438 @default.
- W2783234698 cites W2030570400 @default.
- W2783234698 cites W2032470257 @default.
- W2783234698 cites W2033831542 @default.
- W2783234698 cites W2035157670 @default.
- W2783234698 cites W2038002333 @default.
- W2783234698 cites W2038120115 @default.
- W2783234698 cites W2043918925 @default.
- W2783234698 cites W2044195886 @default.
- W2783234698 cites W2044245854 @default.
- W2783234698 cites W2045942081 @default.
- W2783234698 cites W2046489983 @default.
- W2783234698 cites W2050261470 @default.
- W2783234698 cites W2052104907 @default.
- W2783234698 cites W2055830009 @default.
- W2783234698 cites W2056292153 @default.
- W2783234698 cites W2057926794 @default.
- W2783234698 cites W2060357443 @default.
- W2783234698 cites W2062897718 @default.