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- W2783240324 abstract "In the developing Drosophila eye the centrioles of the differentiating retinal cells are not surrounded by the microtubule nucleating γ-tubulin suggesting that they are unable to organize functional microtubule organizing centers. Consistent with this idea Cnn and Spd-2, involved in γ-tubulin recruitment, and the scaffold protein Plp that plays a role in the organization of the pericentriolar material are lost in the third larval stage. However, the centrioles maintain their structural integrity and both the parents accumulate Asl and Ana1. Although the loading of Asl points to the acquisition of the motherhood condition, the daughter centrioles failed to recruit Plk4 and do not duplicate. However, it is surprising that also the mother centrioles that accumulate Plk4 never duplicate. This suggests that the loading of Plk4 is not sufficient, in this system, to allow centriole duplication. By half of the pupal life the centriole number decreases and structural defects, ranging from incomplete or lacking B-tubules, are detected. Asl, Ana1 and Sas-4 are still present, suggesting that the centriole integrity does not depend on these proteins." @default.
- W2783240324 created "2018-01-26" @default.
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- W2783240324 date "2018-01-01" @default.
- W2783240324 modified "2023-09-23" @default.
- W2783240324 title "The developing Drosophila eye: an oncoming model to study centriole reduction" @default.
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- W2783240324 cites W1964496691 @default.
- W2783240324 cites W1965089979 @default.
- W2783240324 cites W1967897970 @default.
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- W2783240324 cites W1971667392 @default.
- W2783240324 cites W1977721021 @default.
- W2783240324 cites W1978538263 @default.
- W2783240324 cites W1991631964 @default.
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- W2783240324 doi "https://doi.org/10.1242/jcs.211441" @default.
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