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- W2783252772 abstract "Introduction: The objective of our study was to describe and analyse the PCCRCs (Post-Colonoscopy Colorectal Cancers) and related endoscopist risk factors in our regional screening programme. Method: This was a population-based retrospective cohort study. PCCRC was defined as colorectal adenocarcinoma diagnosed between six and sixty months post colonoscopy. All individuals between the ages of 50-74 who participated in the Isere Colorectal Cancer Screening Programme between the dates of 1st January 2002 to 31st December 2013 were studied. We analysed the endoscopist-related PCCRC risk factors of the 62 gastroenterologists who had carried out at least 30 colonoscopies during this period. Results: There were 10557 negative colonscopies performed, 6249 NPC, 620 SC, 15 PCCRC and 711 gFOBT IC. Amongst the PCCRCs there was an average age of 67.1, 73% affected men, 53% of the PCCRCs were in the distal colon. PCCRC comprised 1.1% (95% CI 0.7% to 1.8%) of all CRC diagnosed in the screening programme in the period, with an incidence rate of 0.41 (95% CI 0.21 to 0.71) per 1000 person years. 41% of PCCRCs related to missed cancers, 29% new cancers, 21% failed biopsy detection, and 6% incomplete removal. An inverse linear trend was noted between ADR and the number of PCCRCs per gastroenterologist. The average ADR was 30% and ranged from 11% to 49%. Conclusion: The PCCRC prevalence and incident rate were very low. Overall ADRs were satisfactory however significant heterogeneity was present. Decreasing this heterogeneity should decrease the number of interval cancers in the region." @default.
- W2783252772 created "2018-01-26" @default.
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- W2783252772 date "2017-11-06" @default.
- W2783252772 modified "2023-09-27" @default.
- W2783252772 title "12 year study of the prevalence, risk factors and characteristics of Interval colorectal cancers after negative colonoscopy performed for a positive gFOBT in a screening programme in Isère (France) from 2002 - 2013" @default.
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