Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783256772> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2783256772 endingPage "e22032" @default.
- W2783256772 startingPage "e22032" @default.
- W2783256772 abstract "Carbonic anhydrases (CAs) play an important function in various physiological and pathological processes. Therefore, many researchers work in this field in order to design and synthesize new drugs. Both inhibitors and activators of CAs, which are associated with the diagnosis and treatment of many diseases, are very important. The emergence of the use of CA activators in the treatment of Alzheimer has led many scholars to work on this issue. In this study, CA activators and inhibitors are determined. The crown ethers compounds (1, 2, 3, 6, 7, 8, and 9) were found to cause activation on enzyme activities of hCA I and II. The AC50 values on hCA I and II of the compounds are in the range of 4.6565-374.979 μM. The 4 (IC50 ; 1.301 and 3.215 μM for hCA I and II) and 5 (IC50 ; 73.96 and 378.5 μM for hCA I and II) compounds were found to cause inhibition on enzyme activities of hCA I and II." @default.
- W2783256772 created "2018-01-26" @default.
- W2783256772 creator A5034860212 @default.
- W2783256772 creator A5045479147 @default.
- W2783256772 creator A5058933983 @default.
- W2783256772 creator A5068652603 @default.
- W2783256772 creator A5071325210 @default.
- W2783256772 date "2018-01-12" @default.
- W2783256772 modified "2023-09-23" @default.
- W2783256772 title "The determination of the carbonic anhydrases activators<i>in vitro</i>effect of mixed donor crown ethers" @default.
- W2783256772 cites W1497915593 @default.
- W2783256772 cites W1513087030 @default.
- W2783256772 cites W1966962350 @default.
- W2783256772 cites W1970221679 @default.
- W2783256772 cites W1978887142 @default.
- W2783256772 cites W1994652450 @default.
- W2783256772 cites W2001705855 @default.
- W2783256772 cites W2003743523 @default.
- W2783256772 cites W2015304568 @default.
- W2783256772 cites W2022428162 @default.
- W2783256772 cites W2023054421 @default.
- W2783256772 cites W2035873039 @default.
- W2783256772 cites W2044582728 @default.
- W2783256772 cites W2045002975 @default.
- W2783256772 cites W2046895642 @default.
- W2783256772 cites W2054155042 @default.
- W2783256772 cites W2062983773 @default.
- W2783256772 cites W2067195259 @default.
- W2783256772 cites W2067822500 @default.
- W2783256772 cites W2068210639 @default.
- W2783256772 cites W2077635615 @default.
- W2783256772 cites W2080118439 @default.
- W2783256772 cites W2086688871 @default.
- W2783256772 cites W2088672673 @default.
- W2783256772 cites W2100837269 @default.
- W2783256772 cites W2108697687 @default.
- W2783256772 cites W2153237991 @default.
- W2783256772 cites W2154660194 @default.
- W2783256772 cites W2165819889 @default.
- W2783256772 cites W2186278081 @default.
- W2783256772 cites W2238130428 @default.
- W2783256772 cites W2409029369 @default.
- W2783256772 cites W2510043997 @default.
- W2783256772 cites W2550716650 @default.
- W2783256772 cites W2611517482 @default.
- W2783256772 cites W2740568926 @default.
- W2783256772 cites W4237548661 @default.
- W2783256772 cites W4293247451 @default.
- W2783256772 cites W64262931 @default.
- W2783256772 cites W94314792 @default.
- W2783256772 doi "https://doi.org/10.1002/jbt.22032" @default.
- W2783256772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29327806" @default.
- W2783256772 hasPublicationYear "2018" @default.
- W2783256772 type Work @default.
- W2783256772 sameAs 2783256772 @default.
- W2783256772 citedByCount "7" @default.
- W2783256772 countsByYear W27832567722020 @default.
- W2783256772 countsByYear W27832567722021 @default.
- W2783256772 countsByYear W27832567722022 @default.
- W2783256772 countsByYear W27832567722023 @default.
- W2783256772 crossrefType "journal-article" @default.
- W2783256772 hasAuthorship W2783256772A5034860212 @default.
- W2783256772 hasAuthorship W2783256772A5045479147 @default.
- W2783256772 hasAuthorship W2783256772A5058933983 @default.
- W2783256772 hasAuthorship W2783256772A5068652603 @default.
- W2783256772 hasAuthorship W2783256772A5071325210 @default.
- W2783256772 hasConcept C181199279 @default.
- W2783256772 hasConcept C185592680 @default.
- W2783256772 hasConcept C202751555 @default.
- W2783256772 hasConcept C2775914622 @default.
- W2783256772 hasConcept C2777752497 @default.
- W2783256772 hasConcept C55493867 @default.
- W2783256772 hasConceptScore W2783256772C181199279 @default.
- W2783256772 hasConceptScore W2783256772C185592680 @default.
- W2783256772 hasConceptScore W2783256772C202751555 @default.
- W2783256772 hasConceptScore W2783256772C2775914622 @default.
- W2783256772 hasConceptScore W2783256772C2777752497 @default.
- W2783256772 hasConceptScore W2783256772C55493867 @default.
- W2783256772 hasIssue "3" @default.
- W2783256772 hasLocation W27832567721 @default.
- W2783256772 hasLocation W27832567722 @default.
- W2783256772 hasOpenAccess W2783256772 @default.
- W2783256772 hasPrimaryLocation W27832567721 @default.
- W2783256772 hasRelatedWork W1619794196 @default.
- W2783256772 hasRelatedWork W2003544140 @default.
- W2783256772 hasRelatedWork W2015280585 @default.
- W2783256772 hasRelatedWork W2069584306 @default.
- W2783256772 hasRelatedWork W2092432701 @default.
- W2783256772 hasRelatedWork W2124499287 @default.
- W2783256772 hasRelatedWork W2176886045 @default.
- W2783256772 hasRelatedWork W2477939661 @default.
- W2783256772 hasRelatedWork W4200320620 @default.
- W2783256772 hasRelatedWork W4249578969 @default.
- W2783256772 hasVolume "32" @default.
- W2783256772 isParatext "false" @default.
- W2783256772 isRetracted "false" @default.
- W2783256772 magId "2783256772" @default.
- W2783256772 workType "article" @default.