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- W278326710 abstract "This chapter examines the complexity and diversity of polysomal and informosomal mRNA from Chinese hamster cells. In eucaryotic cells, a fraction of the cytoplasmic polyadenylated mRNA population is not associated with ribosomes. These ribosome-free ribonucleoproteins (informosomes) are thought to play a role in control at the translational level. Early development of the fertilized egg involves programmed utilization of informosomes. Distribution of mRNAs between polysomal and informosomal fractions can change more rapidly than the rate of mRNA synthesis. Some mRNAs can shift from one fraction to the other under the appropriate stimulus. There is no information on the sequence complexity of informosomal mRNA and little data on the degree of sequence diversity between polysomal and informosomal mRNAs. The chapter presents results of work obtained from annealing cDNA copies of polyadenylated mRNA to a vast excess of template mRNA from Chinese hamster cells. Homologous annealing reactions showed that polysomal and informosomal mRNA populations had similar complexities. The most abundant informosomal mRNA contained only ∼ 19% the number of different species comprising the most abundant polysomal mRNA." @default.
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- W278326710 date "1979-01-01" @default.
- W278326710 modified "2023-10-18" @default.
- W278326710 title "COMPLEXITY AND DIVERSITY OF POLYSOMAL AND INFORMOSOMAL mRNA FROM CHINESE HAMSTER CELLS Supported by the Division of Biomedical and Environmental Research of the U. S. Department of Energy." @default.
- W278326710 doi "https://doi.org/10.1016/b978-0-12-604450-8.50104-8" @default.
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