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• W2783304284 abstract "Postoperative cognitive dysfunction (POCD) is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expression in hippocampus and prefrontal cortex cerebrospinal fluid after extracorporeal circulation operation in aged rats. We Found that, compared with POCD group, the cognitive function was improved in POCD + Dex group. We speculate that dexmedetomidine could improve the cognitive function after extracorporeal circulation operation in aged rats and A β , p-Tau, and PSD95 protein might have contributed to this favorable outcome." @default.
• W2783304284 created "2018-01-26" @default.
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• W2783304284 date "2018-01-01" @default.
• W2783304284 modified "2023-10-16" @default.
• W2783304284 title "The Effect of Dexmedetomidine on Cognitive Function and Protein Expression of A<i>β</i>, p-Tau, and PSD95 after Extracorporeal Circulation Operation in Aged Rats" @default.
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• W2783304284 doi "https://doi.org/10.1155/2018/4014021" @default.
• W2783304284 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5820664" @default.
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