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- W2783331395 abstract "Abstract Pure mesenchymal tumours of the uterus broadly comprise two major categories, smooth muscle neoplasms and endometrial stromal neoplasms. Of these the most common tumours are smooth muscle tumours of the uterus, the majority of these are benign and are recognised as leiomyomata routinely. Leiomyosarcoma is the commonest malignant mesenchymal tumour of the uterus accounting for >50% of uterine sarcomas and comprising 1–2% of uterine malignancies. Variants of both benign and malignant tumours are recognised and increasingly, through the evolution of more sophisticated immunohistochemistry and molecular techniques we are aware of the many pitfalls in their diagnosis which will be discussed in this review. The second major category comprises endometrial stromal tumours which has undergone re-classification in the WHO 2014 classification and has been the subject of a recent review in this journal. Despite it being the second most common uterine sarcoma, it is encountered infrequently in routine diagnostic practice, and its benign counterpart is approximately 8× less frequent. Endometrial stromal tumours will not be comprehensively considered in this review, but only in the context of differential diagnosis. This review will attempt to update the reader with recently described entities that may lead to diagnostic confusion and provide a diagnostic approach." @default.
- W2783331395 created "2018-01-26" @default.
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- W2783331395 date "2018-01-01" @default.
- W2783331395 modified "2023-09-26" @default.
- W2783331395 title "Problematic areas and new developments in uterine mesenchymal tumours" @default.
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- W2783331395 doi "https://doi.org/10.1016/j.mpdhp.2017.11.014" @default.
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