FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783393665> ?p ?o ?g. }

• W2783393665 abstract "Abstract Objectives Emotional dysfunction is a common finding in stroke patients. Despite reports on serotonergic involvement in the etiology of poststroke emotional dysfunction ( PSED ), the role of serotonin synthesizing tryptophan hydroxylase 2 ( TPH 2) genes in the development of PSED remains unclear. Methods Genotyping of TPH 2 rs4641528 and rs10879355 was performed from genomic DNA of 383 stroke patients collected previously and stored at −70°C. Potential associations between TPH 2 genes and poststroke depression ( PSD ), poststroke emotional incontinence ( PSEI ), and poststroke anger proneness ( PSAP ) were investigated 3 months poststroke. Results Among the 383 patients, 69 (18%) had PSD , 41 (11%) had PSEI , and 93 (24%) had PSAP . The TPH 2 rs4641528 genotype frequencies differed significantly between patients with and without either PSD or PSEI , although no significant differences were found between the patients with and without PSAP . In multiple logistic regression analysis, PSD was related to the National Institutes of Health Stroke Scale ( NIHSS ) score at admission (95% confidence interval [ CI ]: 1.047–1.230, p < .01), modified Rankin scale score at 3 months (95% CI : 0.135–0.848, p < .05), and TPH 2 rs4641528 C allele (95% CI : 1.039–5.631, p < .05), whereas PSEI was associated only with the NIHSS score at admission (95% CI : 1.053–1.259, p < .01) and the TPH 2 rs4641528 C allele (95% CI : 1.029–11.678, p < .05). Conclusions Our findings suggest that the TPH 2 rs4641528 C allele may play a role in the pathogenesis of PSD and PSEI but not PSAP in Korean stroke patients." @default.
• W2783393665 created "2018-01-26" @default.
• W2783393665 creator A5004921440 @default.
• W2783393665 creator A5016853806 @default.
• W2783393665 creator A5039422552 @default.
• W2783393665 creator A5045370139 @default.
• W2783393665 creator A5048695610 @default.
• W2783393665 creator A5067656534 @default.
• W2783393665 creator A5075503929 @default.
• W2783393665 creator A5077167781 @default.
• W2783393665 date "2018-01-11" @default.
• W2783393665 modified "2023-09-24" @default.
• W2783393665 title "Poststroke emotional disturbances and a tryptophan hydroxylase 2 gene polymorphism" @default.
• W2783393665 cites W156936430 @default.
• W2783393665 cites W1976590570 @default.
• W2783393665 cites W1979188831 @default.
• W2783393665 cites W1983411157 @default.
• W2783393665 cites W1988811691 @default.
• W2783393665 cites W1993159686 @default.
• W2783393665 cites W1994516975 @default.
• W2783393665 cites W1995058408 @default.
• W2783393665 cites W2003982930 @default.
• W2783393665 cites W2006565353 @default.
• W2783393665 cites W2007838581 @default.
• W2783393665 cites W2011973103 @default.
• W2783393665 cites W2018215345 @default.
• W2783393665 cites W2026951563 @default.
• W2783393665 cites W2032738024 @default.
• W2783393665 cites W2038803365 @default.
• W2783393665 cites W2047091590 @default.
• W2783393665 cites W2054337546 @default.
• W2783393665 cites W2056160062 @default.
• W2783393665 cites W2058702631 @default.
• W2783393665 cites W2068080380 @default.
• W2783393665 cites W2092446347 @default.
• W2783393665 cites W2094298095 @default.
• W2783393665 cites W2100621673 @default.
• W2783393665 cites W2102134933 @default.
• W2783393665 cites W2103994810 @default.
• W2783393665 cites W2104638278 @default.
• W2783393665 cites W2112077456 @default.
• W2783393665 cites W2113042365 @default.
• W2783393665 cites W2123890229 @default.
• W2783393665 cites W2139376785 @default.
• W2783393665 cites W2146809629 @default.
• W2783393665 cites W2147548472 @default.
• W2783393665 cites W2148919746 @default.
• W2783393665 cites W2157106133 @default.
• W2783393665 cites W2162969812 @default.
• W2783393665 cites W2171371063 @default.
• W2783393665 cites W2178627879 @default.
• W2783393665 cites W2529087991 @default.
• W2783393665 cites W2530993234 @default.
• W2783393665 cites W2594371116 @default.
• W2783393665 cites W613134548 @default.
• W2783393665 doi "https://doi.org/10.1002/brb3.892" @default.
• W2783393665 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5822583" @default.
• W2783393665 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29484259" @default.
• W2783393665 hasPublicationYear "2018" @default.
• W2783393665 type Work @default.
• W2783393665 sameAs 2783393665 @default.
• W2783393665 citedByCount "9" @default.
• W2783393665 countsByYear W27833936652018 @default.
• W2783393665 countsByYear W27833936652019 @default.
• W2783393665 countsByYear W27833936652020 @default.
• W2783393665 countsByYear W27833936652021 @default.
• W2783393665 countsByYear W27833936652022 @default.
• W2783393665 countsByYear W27833936652023 @default.
• W2783393665 crossrefType "journal-article" @default.
• W2783393665 hasAuthorship W2783393665A5004921440 @default.
• W2783393665 hasAuthorship W2783393665A5016853806 @default.
• W2783393665 hasAuthorship W2783393665A5039422552 @default.
• W2783393665 hasAuthorship W2783393665A5045370139 @default.
• W2783393665 hasAuthorship W2783393665A5048695610 @default.
• W2783393665 hasAuthorship W2783393665A5067656534 @default.
• W2783393665 hasAuthorship W2783393665A5075503929 @default.
• W2783393665 hasAuthorship W2783393665A5077167781 @default.
• W2783393665 hasBestOaLocation W27833936651 @default.
• W2783393665 hasConcept C104317684 @default.
• W2783393665 hasConcept C126322002 @default.
• W2783393665 hasConcept C127413603 @default.
• W2783393665 hasConcept C135763542 @default.
• W2783393665 hasConcept C137627325 @default.
• W2783393665 hasConcept C139719470 @default.
• W2783393665 hasConcept C149737253 @default.
• W2783393665 hasConcept C156957248 @default.
• W2783393665 hasConcept C15744967 @default.
• W2783393665 hasConcept C162324750 @default.
• W2783393665 hasConcept C170493617 @default.
• W2783393665 hasConcept C180754005 @default.
• W2783393665 hasConcept C2775864247 @default.
• W2783393665 hasConcept C2775951788 @default.
• W2783393665 hasConcept C2776867660 @default.
• W2783393665 hasConcept C2780645631 @default.
• W2783393665 hasConcept C2780931571 @default.
• W2783393665 hasConcept C3020199598 @default.
• W2783393665 hasConcept C31467283 @default.
• W2783393665 hasConcept C37000724 @default.
• W2783393665 hasConcept C44249647 @default.
• W2783393665 hasConcept C541997718 @default.

• next