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- W2783403853 abstract "Metabolite profile, antioxidant and antinociceptive activities of Syringa vulgaris bark and leaf methanolic extracts were investigated. By means of HPLC-DAD-ESI-TOF and HPLC-DAD-ESI-MS/MS, a total of 33 phenolics were identified, including 15 secoiridoids, 6 phenylpropanoids, 3 flavonoids, 3 lignans and 6 low molecular weight phenols. Validated quantitative analysis show that syringin (2.52%) and rutin (1.13%) are the main phenolic compounds in bark and leaf, respectively. Notable radical scavenging and antinociceptive activities of the bark and leaf extracts were confirmed by in vitro DPPH● and ABTS●+ assays and by in vivo hot-plate method in mice, respectively. Our results could lay the scientific basic of future clinical perspectives of lilac bark and leaf." @default.
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- W2783403853 date "2018-01-16" @default.
- W2783403853 modified "2023-10-06" @default.
- W2783403853 title "Phenolic composition, antioxidant and antinociceptive activities of <i>Syringa vulgaris</i> L. bark and leaf extracts" @default.
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- W2783403853 doi "https://doi.org/10.1080/14786419.2018.1425855" @default.
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