Matches in SemOpenAlex for { <https://semopenalex.org/work/W2783451181> ?p ?o ?g. }
- W2783451181 endingPage "475" @default.
- W2783451181 startingPage "471" @default.
- W2783451181 abstract "Coronary artery disease (CAD) cannot be sufficiently explained by the presence of traditional risk factors. Cathepsin D has been proposed to serve as a surrogate marker of atherosclerosis but its alterations in CAD patients have not been studied.To evaluate serum cathepsin D concentrations in relation to the presence and severity of CAD.A total of 104 subjects were recruited; 71 patients with suspected CAD and 33 healthy subjects. Thirty-four patients had >50% coronary stenosis of at least one artery (CAD+); the remaining 37 patients had <50% stenosis (CAD-) based on angiography. CAD+ patients were sub-divided into three sub-groups with single (SVD; n=15), double (2VD; n=9), and triple vessel (3VD; n=10) disease. Serum soluble cathepsin D concentrations were determined using an enzyme-linked immunosorbent assay (ELISA).Serum cathepsin D concentrations were significantly higher in the CAD+ compared with healthy control (p=0.016) but not CAD- group (p=0.098). Within the CAD+ group, patients with 3VD had significantly higher serum cathepsin D concentrations compared with the SVD group (p=0.025), and also compared with the CAD- (p=0.011) and SVD (p=0.001) groups. No significant associations were found between serum cathepsin D concentrations and potential confounders including age, sex, blood pressure, smoking history and dyslipidemia.Serum cathepsin D concentrations may be associated with the presence of CAD." @default.
- W2783451181 created "2018-01-26" @default.
- W2783451181 creator A5006098830 @default.
- W2783451181 creator A5006669880 @default.
- W2783451181 creator A5012388493 @default.
- W2783451181 creator A5021676783 @default.
- W2783451181 creator A5036163332 @default.
- W2783451181 creator A5049899353 @default.
- W2783451181 creator A5050407515 @default.
- W2783451181 creator A5080572893 @default.
- W2783451181 creator A5085465720 @default.
- W2783451181 date "2018-07-01" @default.
- W2783451181 modified "2023-09-29" @default.
- W2783451181 title "Evaluation of serum cathepsin D concentrations in coronary artery disease" @default.
- W2783451181 cites W1006559644 @default.
- W2783451181 cites W1584891948 @default.
- W2783451181 cites W194307109 @default.
- W2783451181 cites W1979313091 @default.
- W2783451181 cites W1998593025 @default.
- W2783451181 cites W2002263377 @default.
- W2783451181 cites W2010701670 @default.
- W2783451181 cites W2012083107 @default.
- W2783451181 cites W2013539124 @default.
- W2783451181 cites W2022948423 @default.
- W2783451181 cites W2025039190 @default.
- W2783451181 cites W2027481161 @default.
- W2783451181 cites W2030241666 @default.
- W2783451181 cites W2046980287 @default.
- W2783451181 cites W2047177657 @default.
- W2783451181 cites W2052671730 @default.
- W2783451181 cites W2055508645 @default.
- W2783451181 cites W2065886331 @default.
- W2783451181 cites W2068741629 @default.
- W2783451181 cites W2075782700 @default.
- W2783451181 cites W2076409217 @default.
- W2783451181 cites W2078846752 @default.
- W2783451181 cites W2079642197 @default.
- W2783451181 cites W2081678895 @default.
- W2783451181 cites W2093932892 @default.
- W2783451181 cites W2112355597 @default.
- W2783451181 cites W2112360098 @default.
- W2783451181 cites W2112644193 @default.
- W2783451181 cites W2119193879 @default.
- W2783451181 cites W2122308023 @default.
- W2783451181 cites W2127409551 @default.
- W2783451181 cites W2127589060 @default.
- W2783451181 cites W2143153660 @default.
- W2783451181 cites W2147968849 @default.
- W2783451181 cites W2151711434 @default.
- W2783451181 cites W2157433273 @default.
- W2783451181 cites W2172157091 @default.
- W2783451181 cites W2187863746 @default.
- W2783451181 cites W2290840312 @default.
- W2783451181 cites W4240900378 @default.
- W2783451181 doi "https://doi.org/10.1016/j.ihj.2018.01.003" @default.
- W2783451181 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6117802" @default.
- W2783451181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30170638" @default.
- W2783451181 hasPublicationYear "2018" @default.
- W2783451181 type Work @default.
- W2783451181 sameAs 2783451181 @default.
- W2783451181 citedByCount "8" @default.
- W2783451181 countsByYear W27834511812020 @default.
- W2783451181 countsByYear W27834511812021 @default.
- W2783451181 countsByYear W27834511812022 @default.
- W2783451181 countsByYear W27834511812023 @default.
- W2783451181 crossrefType "journal-article" @default.
- W2783451181 hasAuthorship W2783451181A5006098830 @default.
- W2783451181 hasAuthorship W2783451181A5006669880 @default.
- W2783451181 hasAuthorship W2783451181A5012388493 @default.
- W2783451181 hasAuthorship W2783451181A5021676783 @default.
- W2783451181 hasAuthorship W2783451181A5036163332 @default.
- W2783451181 hasAuthorship W2783451181A5049899353 @default.
- W2783451181 hasAuthorship W2783451181A5050407515 @default.
- W2783451181 hasAuthorship W2783451181A5080572893 @default.
- W2783451181 hasAuthorship W2783451181A5085465720 @default.
- W2783451181 hasBestOaLocation W27834511811 @default.
- W2783451181 hasConcept C126322002 @default.
- W2783451181 hasConcept C134018914 @default.
- W2783451181 hasConcept C151701858 @default.
- W2783451181 hasConcept C164705383 @default.
- W2783451181 hasConcept C167844969 @default.
- W2783451181 hasConcept C173633252 @default.
- W2783451181 hasConcept C181199279 @default.
- W2783451181 hasConcept C194789388 @default.
- W2783451181 hasConcept C2778096610 @default.
- W2783451181 hasConcept C2778213512 @default.
- W2783451181 hasConcept C2779134260 @default.
- W2783451181 hasConcept C55493867 @default.
- W2783451181 hasConcept C71924100 @default.
- W2783451181 hasConcept C86803240 @default.
- W2783451181 hasConcept C90924648 @default.
- W2783451181 hasConceptScore W2783451181C126322002 @default.
- W2783451181 hasConceptScore W2783451181C134018914 @default.
- W2783451181 hasConceptScore W2783451181C151701858 @default.
- W2783451181 hasConceptScore W2783451181C164705383 @default.
- W2783451181 hasConceptScore W2783451181C167844969 @default.
- W2783451181 hasConceptScore W2783451181C173633252 @default.
- W2783451181 hasConceptScore W2783451181C181199279 @default.