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- W2783459161 abstract "Significance Cell migration in multicellular organisms is crucial for embryonic development, immune responses, organ homeostasis, tissue regeneration, and tumor metastasis. However, mechanisms of cell locomotion in tissues are elusive. Here we report that single mammalian cells generate extracellular and membranous cytocapsular tubes as highways for directed cell transportation. Cytocapsular tubes interconnect and form tubular networks for directed cell transportation in multiple directions. Increased eukaryotic translation initiation factor eIF4E-mediated cap-dependent translation initiation promotes cytocapsular tube development. This study reveals that cytocapsular tubes provide membranous tubes for directed cell translocation." @default.
- W2783459161 created "2018-01-26" @default.
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- W2783459161 date "2018-01-16" @default.
- W2783459161 modified "2023-09-25" @default.
- W2783459161 title "Cytocapsular tubes conduct cell translocation" @default.
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- W2783459161 doi "https://doi.org/10.1073/pnas.1717910115" @default.
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